FOXO3a in cancer drug resistance

Y Liu, Y Wang, X Li, Y Jia, J Wang, X Ao - Cancer Letters, 2022 - Elsevier
Cancer is one of the major causes of death and a significant obstacle to increasing life
expectancy worldwide. Chemotherapy remains the first-line adjuvant therapeutic option for …

SRC kinase-mediated signaling pathways and targeted therapies in breast cancer

J Luo, H Zou, Y Guo, T Tong, L Ye, C Zhu, L Deng… - Breast Cancer …, 2022 - Springer
Breast cancer (BC) has been ranked the most common malignant tumor throughout the
world and is also a leading cause of cancer-related deaths among women. SRC family …

Exosome-based nanomedicine for cancer treatment by targeting inflammatory pathways: current status and future perspectives

MA Ansari, M Thiruvengadam, B Venkidasamy… - Seminars in cancer …, 2022 - Elsevier
Cancer is one of the dreadful diseases worldwide. Surgery, radiation and chemotherapy, are
the three basic standard modes of cancer treatment. However, difficulties in cancer treatment …

Predictive biomarkers of response to neoadjuvant chemotherapy in breast cancer: current and future perspectives for precision medicine

F Derouane, C van Marcke, M Berlière, A Gerday… - Cancers, 2022 - mdpi.com
Simple Summary Despite the increased use of neoadjuvant chemotherapy in the early
setting of breast cancer, there is a clinical need for predictive markers of response in daily …

Molecular classification, treatment, and genetic biomarkers in triple-negative breast cancer: a review

B Lu, E Natarajan… - … in Cancer Research …, 2023 - journals.sagepub.com
Breast cancer is the most common malignancy and the second most common cause of
cancer-related mortality in women. Triple-negative breast cancers do not express estrogen …

Asparagine endopeptidase regulates lysosome homeostasis via modulating endomembrane phosphoinositide composition

L Yao, GH Zi, M He, Y Xu, L Wang, B Peng - Cell Death & Disease, 2024 - nature.com
Asparagine endopeptidase (AEP) is ubiquitously expressed in both physiological and
pathological contexts, yet its precise role and functional mechanism in breast cancer remain …

Updates on triple-negative breast cancer in type 2 diabetes mellitus patients: from risk factors to diagnosis, biomarkers and therapy

S Matou-Nasri, M Aldawood, F Alanazi, AL Khan - Diagnostics, 2023 - mdpi.com
Triple-negative breast cancer (TNBC) is usually the most malignant and aggressive
mammary epithelial tumor characterized by the lack of expression for estrogen receptors …

New achievements for the treatment of triple-negative breast cancer

A Catalano, D Iacopetta, J Ceramella, A Mariconda… - Applied Sciences, 2022 - mdpi.com
Triple-negative breast cancer (TNBC) constitutes a heterogeneous group of malignancies
that are often aggressive and associated with a poor prognosis. The development of new …

[HTML][HTML] Changes in the immune landscape of TNBC after neoadjuvant chemotherapy: Correlation with relapse

MR Moamin, R Allen, SL Woods, JE Brown… - Frontiers in …, 2023 - frontiersin.org
Introduction Patients with high-risk, triple negative breast cancer (TNBC) often receive
neoadjuvant chemotherapy (NAC) alone or with immunotherapy. Various single-cell and …

[HTML][HTML] Ferroptosis induction via targeting metabolic alterations in triple-negative breast cancer

Y Wang, Y Sun, F Wang, H Wang, J Hu - Biomedicine & Pharmacotherapy, 2023 - Elsevier
Triple-negative breast cancer (TNBC), the most aggressive form of breast cancer, presents
severe threats to women's health. Therefore, it is critical to find novel treatment approaches …