Enormous progress has been made in the last half-century in the management of diseases
closely integrated with excess body weight, such as hypertension, adult-onset diabetes and …

The central nervous system (CNS) receives information from afferent neurons, circulating
hormones, and absorbed nutrients and integrates this information to orchestrate the actions …

Obesity and its comorbidities, including type 2 diabetes mellitus, cardiovascular disease,
heart failure and non-alcoholic liver disease are a major health and economic burden with …

The gut–brain axis refers to the bidirectional communication between the gut and the brain.
Four information carriers (vagal and spinal afferent neurons, immune mediators such as …

In November 1955, Geoffrey Harris published a paper based on the Christian A Herter
Lecture he had given earlier that year at Johns Hopkins University in Baltimore, MD, USA …

Dietary protein enhances satiety and promotes weight loss, but the mechanisms by which
appetite is affected remain unclear. We investigated the role of gut hormones, key regulators …

Our understanding of the physiological systems that regulate food intake and body weight
has increased immensely over the past decade. Brain centres, including the hypothalamus …

Obesity is one of the major challenges for public health in 21st century, with 1.9 billion
people being considered as overweight and 600 million as obese. There are certain …

Obesity represents the most prevalent nutritional problem worldwide which in the long run
predisposes to development of diabetes mellitus, hypertension, endometrial carcinoma …

The role of gastrointestinal hormones in the regulation of appetite is reviewed. The
gastrointestinal tract is the largest endocrine organ in the body. Gut hormones function to …