Planar cell polarity (PCP) is an essential feature of animal tissues, whereby distinct polarity
is established within the plane of a cell sheet. Tissue-wide establishment of PCP is driven by …

There are approximately 800 annotated G protein–coupled receptor (GPCR) genes, making
these membrane receptors members of the most abundant gene family in the human …

Motile cilia are hair-like cell extensions that beat periodically to generate fluid flow along
various epithelial tissues within the body. In dense multiciliated carpets, cilia were shown to …

In vertebrates, multiciliated cells (MCCs) are terminally differentiated cells that line the
airway tracts, brain ventricles, and reproductive ducts. Each MCC contains dozens to …

Many animal cells assemble single cilia involved in motile and/or sensory functions. In
contrast, multiciliated cells (MCCs) assemble up to 300 motile cilia that beat in a coordinate …

Polarization of node cells along the anterior-posterior axis of mouse embryos is responsible
for left-right symmetry breaking. How node cells become polarized has remained unknown …

Motile cilia are dynamic hair-like structures covering epithelial surfaces in multiple organs.
The periodic coordinated beating of cilia creates waves propagating along the surface …

Cell polarity refers to the asymmetric distribution of signaling molecules, cellular organelles,
and cytoskeleton in a cell. Neural progenitors and neurons are highly polarized cells in …

The conduits of life; the animal oviducts and human fallopian tubes are of paramount
importance for reproduction in amniotes. They connect the ovary with the uterus and are …

Embryogenesis is a highly complex and dynamic process, and its visualization is crucial for
understanding basic physiological processes during development and for identifying and …