Psychedelics in psychiatry: neuroplastic, immunomodulatory, and neurotransmitter mechanisms

A Inserra, D De Gregorio, G Gobbi, M Nader - Pharmacological Reviews, 2021 - Elsevier
Mounting evidence suggests safety and efficacy of psychedelic compounds as potential
novel therapeutics in psychiatry. Ketamine has been approved by the Food and Drug …

Psychedelics

DE Nichols, EL Barker - Pharmacological reviews, 2016 - Elsevier
Psychedelics (serotonergic hallucinogens) are powerful psychoactive substances that alter
perception and mood and affect numerous cognitive processes. They are generally …

Designer drugs: mechanism of action and adverse effects

D Luethi, ME Liechti - Archives of toxicology, 2020 - Springer
Psychoactive substances with chemical structures or pharmacological profiles that are
similar to traditional drugs of abuse continue to emerge on the recreational drug market …

Receptor interaction profiles of novel psychoactive tryptamines compared with classic hallucinogens

A Rickli, OD Moning, MC Hoener, ME Liechti - European …, 2016 - Elsevier
The present study investigated interactions between the novel psychoactive tryptamines
DiPT, 4-OH-DiPT, 4-OH-MET, 5-MeO-AMT, and 5-MeO-MiPT at monoamine receptors and …

Recent advances in the neuropsychopharmacology of serotonergic hallucinogens

AL Halberstadt - Behavioural brain research, 2015 - Elsevier
Abstract Serotonergic hallucinogens, such as (+)-lysergic acid diethylamide, psilocybin, and
mescaline, are somewhat enigmatic substances. Although these drugs are derived from …

Ayahuasca: Pharmacology, neuroscience and therapeutic potential

E Domínguez-Clavé, J Soler, M Elices, JC Pascual… - Brain research …, 2016 - Elsevier
Ayahuasca is the Quechua name for a tea obtained from the vine Banisteriopsis caapi, and
used for ritual purposes by the indigenous populations of the Amazon. The use of a variation …

N, N-dimethyltryptamine (DMT), an endogenous hallucinogen: past, present, and future research to determine its role and function

SA Barker - Frontiers in neuroscience, 2018 - frontiersin.org
This report provides a historical overview of research concerning the endogenous
hallucinogen N, N-dimethyltryptamine (DMT), focusing on data regarding its biosynthesis …

Neuropharmacology of N, N-dimethyltryptamine

TM Carbonaro, MB Gatch - Brain research bulletin, 2016 - Elsevier
Abstract N, N-dimethyltryptamine (DMT) is an indole alkaloid widely found in plants and
animals. It is best known for producing brief and intense psychedelic effects when ingested …

The hallucinogenic world of tryptamines: an updated review

AM Araújo, F Carvalho, ML Bastos… - Archives of …, 2015 - Springer
In the area of psychotropic drugs, tryptamines are known to be a broad class of classical or
serotonergic hallucinogens. These drugs are capable of producing profound changes in …

Novel psychoactive substances of interest for psychiatry

F Schifano, L Orsolini, G Duccio Papanti… - World …, 2015 - Wiley Online Library
Novel psychoactive substances include synthetic cannabinoids, cathinone derivatives,
psychedelic phenethylamines, novel stimulants, synthetic opioids, tryptamine derivatives …