Inflammasomes and IL-1 family cytokines in SARS-CoV-2 infection: from prognostic marker to therapeutic agent
J Declercq, E De Leeuw, BN Lambrecht - Cytokine, 2022 - Elsevier
Despite global vaccination programs, infections with severe acute respiratory syndrome
coronavirus-2 (SARS-CoV-2) continue to cause severe disease with significant morbidity …
coronavirus-2 (SARS-CoV-2) continue to cause severe disease with significant morbidity …
Pyroptosis and its role in SARS-CoV-2 infection
ZA Bittner, M Schrader, SE George, R Amann - Cells, 2022 - mdpi.com
The pore-forming inflammatory cell death pathway, pyroptosis, was first described in the
early 1990s and its role in health and disease has been intensively studied since. The …
early 1990s and its role in health and disease has been intensively studied since. The …
Colchicine drug interaction errors and misunderstandings: recommendations for improved evidence-based management
PD Hansten, MS Tan, JR Horn, A Gomez-Lumbreras… - Drug Safety, 2023 - Springer
Colchicine is useful for the prevention and treatment of gout and a variety of other disorders.
It is a substrate for CYP3A4 and P-glycoprotein (P-gp), and concomitant administration with …
It is a substrate for CYP3A4 and P-glycoprotein (P-gp), and concomitant administration with …
Clinical update on COVID-19 for the emergency and critical care clinician: Medical management
Introduction Coronavirus disease of 2019 (COVID-19) has resulted in millions of cases
worldwide. As the pandemic has progressed, the understanding of this disease has evolved …
worldwide. As the pandemic has progressed, the understanding of this disease has evolved …
Effect of colchicine on the outcomes of patients with COVID-19: a systematic review and meta-analysis of randomised controlled trials
SH Lan, CK Hsu, CC Lai, SP Chang, LC Lu… - Annals of …, 2022 - Taylor & Francis
Aim This meta-analysis aimed to assess the usefulness of colchicine in patients with COVID-
19. Methods PubMed, Web of Science, Ovid MEDLINE, the Cochrane Library, Embase, and …
19. Methods PubMed, Web of Science, Ovid MEDLINE, the Cochrane Library, Embase, and …
Covid-19, an unfinished story
Y Buisson - La Presse Médicale, 2022 - Elsevier
The Covid-19 pandemic appeared in China in December 2019 as a cluster of transmissible
pneumonia caused by a new betacoronavirus. On March 11, 2020, the World Health …
pneumonia caused by a new betacoronavirus. On March 11, 2020, the World Health …
Failed clinical trials on COVID-19 acute respiratory distress syndrome in hospitalized patients: common oversights and streamlining the development of clinically …
Introduction The coronavirus disease 2019 (COVID-19) pandemic has put a strain on global
healthcare systems. Despite admirable efforts to develop rapidly new pharmacotherapies …
healthcare systems. Despite admirable efforts to develop rapidly new pharmacotherapies …
Colchicine and risk of hospitalization due to COVID‐19: A population‐based study
M Sáenz‐Aldea, Á Salgado‐Barreira… - Journal of Medical …, 2023 - Wiley Online Library
Colchicine is one of the most widely studied and best‐known anti‐inflammatory treatments.
This study aimed to assess the effect of colchicine on risk of hospitalization due to COVID …
This study aimed to assess the effect of colchicine on risk of hospitalization due to COVID …
Potential role of colchicine in combating COVID-19 cytokine storm and its ability to inhibit protease enzyme of SARS-CoV-2 as conferred by molecular docking …
Despite the advance in the management of Coronavirus disease 2019 (COVID-19), the
global pandemic is still ongoing with a massive health crisis. COVID-19 manifestations may …
global pandemic is still ongoing with a massive health crisis. COVID-19 manifestations may …
The evidence from clinical trials on Colchicine and corticosteroids' effect on COVID-19: a systematic review and meta-analysis
AN Bitar, SAS Sulaiman - Current Medical Research and Opinion, 2022 - Taylor & Francis
Objectives With no clear end for the outbreak, identifying the drugs that are effective in
COVID-19's management is of utmost importance to reduce the impact on the general …
COVID-19's management is of utmost importance to reduce the impact on the general …