Ribosome-inactivating proteins (RIPs) are EC3. 2.32. 22 N-glycosidases that recognize a
universally conserved stem-loop structure in 23S/25S/28S rRNA, depurinating a single …

Myocardial infarction and ischemic stroke are the most frequent causes of death or disability
worldwide. Due to their ability to dissolve blood clots, the thrombolytics are frequently used …

The urokinase receptor (uPAR) was originally identified as the membrane receptor of the
serine protease urokinase (uPA), thereby implicated in the plasminogen activation cascade …

This study addresses the environmental risks associated with the accumulation of keratin
waste from poultry, which is resistant to conventional protein degradation methods. To tackle …

Protein-protein interactions play crucial and subtle roles in many biological processes and
modifications of their fine mechanisms generally result in severe diseases. Peptide …

The urokinase receptor (uPAR) is a multifunctional glycosylphosphatidylinositol-anchored
protein that regulates important processes such as gene expression, cell proliferation …

Abstract Background Integrin α3 (ITGA3) gene mutations are associated with Interstitial Lung
disease, Nephrotic syndrome and Epidermolysis bullosa (ILNEB syndrome). To date only six …

The urokinase receptor (uPAR) stimulates cell proliferation by forming a macromolecular
complex with αvβ3 integrin and the epidermal growth factor receptor (EGFR, ErbB1 or …

Mycobacterium tuberculosis causes more than 1 million deaths every year, which is higher
than any other bacterial pathogen. Its success depends on its interaction with the host and …

We previously showed that the kringle domains of plasmin and angiostatin, the N‐terminal
four kringles (K1–4) of plasminogen, directly bind to integrins. Angiostatin blocks tumor …