Sperm selection for ICSI: do we have a winner?

D Baldini, D Ferri, GM Baldini, D Lot, A Catino… - Cells, 2021 - mdpi.com
In assisted reproductive technology (ART), the aim of sperm cells' preparation is to select
competent spermatozoa with the highest fertilization potential and in this context, the …

Sperm selection in assisted reproduction: A review of established methods and cutting-edge possibilities

G Marzano, MS Chiriacò, E Primiceri… - Biotechnology …, 2020 - Elsevier
Male infertility often involves idiopathic or unknown causes, leading to an increasing
demand for assisted reproduction technologies (ART). Conventional sperm sorting …

A treatment approach for couples with disrupted sperm DNA integrity and recurrent ART failure

A Parrella, D Keating, S Cheung, P Xie… - Journal of assisted …, 2019 - Springer
Objective To test a novel method to select spermatozoa with high chromatin integrity. Design
Specimens with high sperm chromatin fragmentation (SCF) were selected by density …

Sperm selection methods in the 21st century

DA Vaughan, D Sakkas - Biology of reproduction, 2019 - academic.oup.com
Natural sperm selection in humans is a rigorous process resulting in the highest quality
sperm reaching, and having an opportunity to fertilize, the oocyte. Relative to other …

Imaging technologies for microfluidic biochips

J Han, U Kang, EY Moon, H Yoo, B Gweon - BioChip Journal, 2022 - Springer
With the growing interest in biochips, numerous efforts have been made to recapitulate a
more reliable and physiologically relevant environment within chips, resulting in significant …

Sperm‐cell DNA fragmentation prediction using label‐free quantitative phase imaging and deep learning

L Noy, I Barnea, SK Mirsky, D Kamber, M Levi… - Cytometry Part …, 2023 - Wiley Online Library
In intracytoplasmic sperm injection (ICSI), a single sperm cell is selected and injected into an
egg. The quality of the chosen sperm and specifically its DNA fragmentation have a …

IVF-on-a-chip: recent advances in microfluidics technology for in vitro fertilization

L Weng - SLAS TECHNOLOGY: Translating Life Sciences …, 2019 - journals.sagepub.com
In vitro fertilization (IVF) has been one of the most exciting modern medical technologies. It
has transformed the landscape of human infertility treatment. However, current IVF …

Disposable paper-based microfluidics for fertility testing

MR Sarabi, D Yigci, MM Alseed, BA Mathyk, B Ata… - IScience, 2022 - cell.com
Fifteen percent of couples of reproductive age suffer from infertility globally and the burden
of infertility disproportionately impacts residents of developing countries. Assisted …

Real-time halo correction in phase contrast imaging

ME Kandel, M Fanous, C Best-Popescu… - Biomedical optics …, 2018 - opg.optica.org
As a label-free, nondestructive method, phase contrast is by far the most popular microscopy
technique for routine inspection of cell cultures. However, features of interest such as …

Quantitative phase imaging of erythrocytes under microfluidic constriction in a high refractive index medium reveals water content changes

HS Park, WJ Eldridge, WH Yang, M Crose… - Microsystems & …, 2019 - nature.com
Abstract Changes in the deformability of red blood cells can reveal a range of pathologies.
For example, cells which have been stored for transfusion are known to exhibit progressively …