Cytoskeletal crosstalk in cell migration
S Seetharaman, S Etienne-Manneville - Trends in cell biology, 2020 - cell.com
Cell migration is a highly dynamic process driven by the cytoskeleton, which mainly
comprises the actin microfilaments, microtubules, and intermediate filaments. During …
comprises the actin microfilaments, microtubules, and intermediate filaments. During …
[HTML][HTML] Microtubule-severing enzymes: From cellular functions to molecular mechanism
FJ McNally, A Roll-Mecak - The Journal of cell biology, 2018 - ncbi.nlm.nih.gov
Microtubule-severing enzymes generate internal breaks in microtubules. They are
conserved in eukaryotes from ciliates to mammals, and their function is important in diverse …
conserved in eukaryotes from ciliates to mammals, and their function is important in diverse …
[HTML][HTML] Tubulin post-translational modifications and microtubule dynamics
D Wloga, E Joachimiak, H Fabczak - International journal of molecular …, 2017 - mdpi.com
Microtubules are hollow tube-like polymeric structures composed of α, β-tubulin
heterodimers. They play an important role in numerous cellular processes, including …
heterodimers. They play an important role in numerous cellular processes, including …
Microtubules: From understanding their dynamics to using them as potential therapeutic targets
Y Ilan - Journal of cellular physiology, 2019 - Wiley Online Library
Microtubules (MT) and actin microfilaments are dynamic cytoskeleton components involved
in a range of intracellular processes. MTs play a role in cell division, beating of cilia and …
in a range of intracellular processes. MTs play a role in cell division, beating of cilia and …
L‐leucine promotes axonal outgrowth and regeneration via mTOR activation
C Ma, L Teng, G Lin, B Guo, R Zhuo, X Qian… - The FASEB …, 2021 - Wiley Online Library
Discovering safe and effective drugs that promote neuron regeneration is an essential
strategy for the recovery of central nervous system injuries. In this study, we found that L …
strategy for the recovery of central nervous system injuries. In this study, we found that L …
Molecular basis of vasohibins-mediated detyrosination and its impact on spindle function and mitosis
Abstract α-Tubulin detyrosination, largely catalyzed by vasohibins, is involved in many
microtubule (MT)-related cellular events. In this study, we identified a core heterodimeric …
microtubule (MT)-related cellular events. In this study, we identified a core heterodimeric …
[HTML][HTML] The role of spastin in axon biology
AC Costa, MM Sousa - Frontiers in cell and developmental biology, 2022 - frontiersin.org
Neurons are highly polarized cells with elaborate shapes that allow them to perform their
function. In neurons, microtubule organization—length, density, and dynamics—are …
function. In neurons, microtubule organization—length, density, and dynamics—are …
[HTML][HTML] Differential circular RNA expression profiles following spinal cord injury in rats: a temporal and experimental analysis
R Wu, S Mao, Y Wang, S Zhou, Y Liu, M Liu… - Frontiers in …, 2019 - frontiersin.org
Spinal cord injury (SCI), one of the most severe types of neurological damage, results in
persistent motor and sensory dysfunction and involves complex gene alterations. Circular …
persistent motor and sensory dysfunction and involves complex gene alterations. Circular …
[HTML][HTML] Pulmonary toxicity and proteomic analysis in bronchoalveolar lavage fluids and lungs of rats exposed to copper oxide nanoparticles
JT Kwon, Y Kim, S Choi, B Yoon, HS Kim… - International journal of …, 2022 - mdpi.com
Copper oxide nanoparticles (CuO NPs) were intratracheally instilled into lungs at
concentrations of 0, 0.15, and 1.5 mg/kg bodyweight to 7-week-old Sprague–Dawley rats …
concentrations of 0, 0.15, and 1.5 mg/kg bodyweight to 7-week-old Sprague–Dawley rats …
[HTML][HTML] Cooperation of long noncoding RNA LOC100909675 and transcriptional regulator CTCF modulates Cdk1 transcript to control astrocyte proliferation
R Wu, H Lin, W Zhang, Y Sun, X Qian, G Lin… - Journal of Biological …, 2023 - ASBMB
Astrocyte activation and proliferation contribute to glial scar formation during spinal cord
injury (SCI), which limits nerve regeneration. The long noncoding RNAs (lncRNAs) are …
injury (SCI), which limits nerve regeneration. The long noncoding RNAs (lncRNAs) are …