Synthesis, enzyme inhibition, and in silico studies of Amino Acid Schiff Bases

NA Taş, A Şenocak, P Taslimi, B Tuzun… - Iranian Journal of …, 2024 - ijcce.ac.ir
In this research, novel complexes of Zn (II) were produced using amino acid Schiff bases.
First, new Schiff bases were synthesized from the reaction of 3-methoxy-2 …

Spectroscopic inspection, DFT analysis, biological evaluation and molecular docking studies of new 2-(phenylamino) acetohydrazide hydrazone based-transition …

TI Kashar, SS Hassan, HA El-Boraey - Inorganica Chimica Acta, 2024 - Elsevier
The binuclear Pd (II) and mononuclear Zn (II), Ru (III) and Pt (IV) chelates were synthesized
based on new hydrazone ligand derived from 2-(phenylamino) acetohydrazide and 3-Acetyl …

Pro-Gly based dipeptide containing sulphonamide functionality, their antidiabetic, antioxidant, and anti-inflammatory activities. Synthesis, characterization and …

SI Attah, UC Okoro, SP Singh, CC Eze, CU Ibeji… - Journal of Molecular …, 2022 - Elsevier
The increasing resistance to antidiabetic, antioxidant, and anti-inflammatory drugs are
complex and severe health issues these days, as many drugs available on the market are …

Dehydroacetic acid hydrazones as potent enzyme inhibitors: design, synthesis and computational studies

R Lakhia, N Raghav, R Pundeer - Computational Toxicology, 2022 - Elsevier
The present study offers the work on the hydrazone derivatives of dehydroacetic acid to be
considered for computational and synthetic studies. The hydrazone derivatives of …

[PDF][PDF] Synthesis, Enzyme Inhibition, and in Silico Studies of Amino Acid Schiff Bases

N Akkuş Taş, A Şenocak, P Taslimi, B Tüzün… - Iran. J. Chem. Chem …, 2024 - ijcce.ac.ir
In this research, novel complexes of Zn (II) were produced using amino acid Schiff bases.
First, new Schiff bases were synthesized from the reaction of 3-methoxy-2 …

[PDF][PDF] Experimental and theoretical evidence on the amoebicidal activity of synthesized tRNA-palmitic acid esters

A Aksu, MS Çelik, ZA Polat, AF Yenidünya… - Iran. J. Chem. Chem …, 2024 - ijcce.ac.ir
Synthesis of tRNA-palmitic acid esters was carried out in dimethyl sulfoxide (DMSO) and tert-
butanol,% 20 and% 80 (v/v), respectively, for 24h at 55oC. These conditions have been to …

Synthesis, in silico studies and investigations on antimicrobial, antimalarial activities of p-toluenesulphonamoyl 'Leu-Gly'dipeptide carboxamide derivatives

EL Ayuk, UC Okoro, CU Ibeji, CM Nkambule - Journal of Molecular …, 2023 - Elsevier
Six novel leucine-glycine dipeptide sulphonamide deriavtives were synthesized and
characterized via 1 HNMR, 13 CNMR, FTIR and HRMS spectroscopic techniques. The in …

Synthesis, Crystal structure, photoluminescence properties and quantum mechanics studies of two schiff bases of 2-amino-p-cresol

CU Ibeji, K Ukogu, MT Kelani, FE Ani, NL Obasi… - Journal of Molecular …, 2022 - Elsevier
Abstract The compounds,(E)-2-((2, 5-dimethoxybenzilidene) amino)-4-methylphenol (DMB–
APC) and 2-((E)-((E)-3-(4-methoxyphenyl) allylidene) amino)-4-methylphenol (TPPC) were …

New substituted benzenesulphonamoyl 'Cys-Gly'dipeptide carboxamide derivatives: Design, synthesis, characterization and pharmacological studies

TO Oni, EL Ayuk, UC Okoro - Bioorganic Chemistry, 2024 - Elsevier
Abstract Twelve new sulphonamide (Cys-Gly) dipeptide carboxamide derivatives 17a–17l
were designed, prepared and characterized through spectroscopic techniques and their …

New heterocycles from dehydroacetic acid (DHA). Synthesis, antimicrobial activity, DNA gyrase inhibition, antioxidant activity, and molecular docking study

A Abdel-Aziem, H Abdelmegeed, MS Abdel-Aziz… - Journal of Molecular …, 2025 - Elsevier
Dehydroacetic acid (DHA) is a significant heterocyclic molecule whose derivatives are
highly prevalent. Thus, a new series of heterocyclic derivatives starting from dehydroacetic …