[HTML][HTML] Target specific tight junction modulators

J Brunner, S Ragupathy, G Borchard - Advanced drug delivery reviews, 2021 - Elsevier
Intercellular tight junctions represent a formidable barrier against paracellular drug
absorption at epithelia (eg, nasal, intestinal) and the endothelium (eg, blood–brain barrier) …

Tight junction protein signaling and cancer biology

Z Nehme, N Roehlen, P Dhawan, TF Baumert - Cells, 2023 - mdpi.com
Tight junctions (TJs) are intercellular protein complexes that preserve tissue homeostasis
and integrity through the control of paracellular permeability and cell polarity. Recent …

Airway basal cells, protectors of epithelial walls in health and respiratory diseases

E Ruysseveldt, K Martens, B Steelant - Frontiers in Allergy, 2021 - frontiersin.org
The airway epithelium provides a critical barrier to the outside environment. When its
integrity is impaired, epithelial cells and residing immune cells collaborate to exclude …

Protective effect of berberine against LPS-induced injury in the intestine: a review

F Izadparast, B Riahi-Zajani, F Yarmohammadi… - Cell Cycle, 2022 - Taylor & Francis
Sepsis is a systemic inflammatory condition caused by an unbalanced immunological
response to infection, which affects numerous organs, including the intestines …

A multistrain probiotic improves handgrip strength and functional capacity in patients with COPD: A randomized controlled trial

A Karim, T Muhammad, MS Iqbal, R Qaisar - Archives of gerontology and …, 2022 - Elsevier
Purpose The age-related muscle loss, termed sarcopenia and functional dependency, are
common findings in patients with chronic obstructive pulmonary disease (COPD). However …

Overview of the assessment of endothelial function in humans

PY Chia, A Teo, TW Yeo - Frontiers in Medicine, 2020 - frontiersin.org
The endothelium is recognized to play an important role in various physiological functions
including vascular tone, permeability, anticoagulation, and angiogenesis. Endothelial …

Fecal microbiota transplantation protects the intestinal mucosal barrier by reconstructing the gut microbiota in a murine model of sepsis

X Gai, H Wang, Y Li, H Zhao, C He, Z Wang… - Frontiers in cellular and …, 2021 - frontiersin.org
The gastrointestinal (GI) tract has long been hypothesized to play an integral role in the
pathophysiology of sepsis, and gut microbiota (GM) dysbiosis may be the key factor …

[HTML][HTML] Impact of microplastics on the intestinal microbiota: A systematic review of preclinical evidence

TG de Souza-Silva, IA Oliveira, GG da Silva, FCV Giusti… - Life sciences, 2022 - Elsevier
Aims We systematically review the in vivo preclinical evidence on the impact of microplastics
(MPs) on the intestinal microbiota and morphofunctional changes involving the intestinal …

Necrotic enteritis in chickens: A review of pathogenesis, immune responses and prevention, focusing on probiotics and vaccination

M Alizadeh, B Shojadoost, N Boodhoo… - Animal Health …, 2021 - cambridge.org
Necrotic enteritis (NE), caused by Clostridium perfringens (CP), is one of the most common
of poultry diseases, causing huge economic losses to the poultry industry. This review …

Fecal microbiota transplantation and short-chain fatty acids reduce sepsis mortality by remodeling antibiotic-induced gut microbiota disturbances

X Lou, J Xue, R Shao, Y Yang, D Ning, C Mo… - Frontiers in …, 2023 - frontiersin.org
Objective Sepsis is the leading cause of death in critically ill patients. The gastrointestinal
tract has long been thought to play an important role in the pathophysiology of sepsis …