Effects of curcumin on mitochondria in neurodegenerative diseases

H Bagheri, F Ghasemi, GE Barreto, R Rafiee… - Biofactors, 2020 - Wiley Online Library
Neurodegenerative diseases (NDs) result from progressive deterioration of selectively
susceptible neuron populations in different central nervous system (CNS) regions. NDs are …

Inflammatory mechanisms and oxidative stress as key factors responsible for progression of neurodegeneration: role of brain innate immune system

J Leszek, GE Barreto, K Gasiorowski… - CNS & Neurological …, 2016 - ingentaconnect.com
Chronic inflammation is characterized by longstanding microglial activation followed by
sustained release of inflammatory mediators, which aid in enhanced nitrosative and …

Impact of plant-derived flavonoids on neurodegenerative diseases

SL Costa, VDA Silva, C dos Santos Souza… - Neurotoxicity …, 2016 - Springer
Neurodegenerative disorders have a common characteristic that is the involvement of
different cell types, typically the reactivity of astrocytes and microglia, characterizing gliosis …

Relationship between obesity, Alzheimer's disease, and Parkinson's disease: an astrocentric view

CA Martin-Jiménez, DM Gaitán-Vaca… - Molecular …, 2017 - Springer
Obesity is considered one of the greatest risk to human health and is associated with several
factors including genetic components, diet, and physical inactivity. Recently, the relationship …

Platelet-derived growth factor-BB protects mesenchymal stem cells (MSCs) derived from immune thrombocytopenia patients against apoptosis and senescence and …

J Zhang, F Feng, Q Wang, X Zhu, H Fu… - Stem Cells …, 2016 - academic.oup.com
Immune thrombocytopenia (ITP) is characterized by platelet destruction and megakaryocyte
dysfunction. Mesenchymal stem cells (MSCs) from ITP patients (MSC-ITP) do not exhibit …

Protection by neuroglobin expression in brain pathologies

E Baez, V Echeverria, R Cabezas… - Frontiers in …, 2016 - frontiersin.org
Astrocytes play an important role in physiological, metabolic, and structural functions, and
when impaired, they can be involved in various pathologies including Alzheimer, focal …

Growth factors and neuroglobin in astrocyte protection against neurodegeneration and oxidative stress

R Cabezas, E Baez-Jurado, O Hidalgo-Lanussa… - Molecular …, 2019 - Springer
Neurodegenerative diseases, such as Parkinson and Alzheimer, are among the main public
health issues in the world due to their effects on life quality and high mortality rates. Although …

Antioxidant and neuroprotective properties of non-centrifugal cane sugar and other sugarcane derivatives in an in vitro induced Parkinson's model

J Cifuentes, VA Salazar, M Cuellar, MC Castellanos… - Antioxidants, 2021 - mdpi.com
Non-centrifugal cane sugar (NCS) is a traditional sweetener in most sugarcane regions of
the world. In Colombia, this product has a socio-economic importance due to the extensive …

Concordant and discordant cerebrospinal fluid and plasma cytokine and chemokine responses in mild cognitive impairment and early-stage Alzheimer's disease

SM de la Monte, M Tong, AJ Hapel - Biomedicines, 2023 - mdpi.com
Neuroinflammation may be a pathogenic mediator and biomarker of neurodegeneration at
the boundary between mild cognitive impairment (MCI) and early-stage Alzheimer's disease …

Palmitic acid induces neurotoxicity and gliatoxicity in SH-SY5Y human neuroblastoma and T98G human glioblastoma cells

YW Ng, YH Say - PeerJ, 2018 - peerj.com
Background Obesity-related central nervous system (CNS) pathologies like
neuroinflammation and reactive gliosis are associated with high-fat diet (HFD) related …