Conventional and emerging strategies for the fabrication and functionalization of PDMS-based microfluidic devices
Microfluidics is an emerging and multidisciplinary field that is of great interest to
manufacturers in medicine, biotechnology, and chemistry, as it provides unique tools for the …
manufacturers in medicine, biotechnology, and chemistry, as it provides unique tools for the …
Brain-on-a-chip: Recent advances in design and techniques for microfluidic models of the brain in health and disease
Recent advances in biomaterials, microfabrication, microfluidics, and cell biology have led to
the development of organ-on-a-chip devices that can reproduce key functions of various …
the development of organ-on-a-chip devices that can reproduce key functions of various …
High-throughput organ-on-chip platform with integrated programmable fluid flow and real-time sensing for complex tissue models in drug development workflows
H Azizgolshani, JR Coppeta, EM Vedula, EE Marr… - Lab on a Chip, 2021 - pubs.rsc.org
Drug development suffers from a lack of predictive and human-relevant in vitro models.
Organ-on-chip (OOC) technology provides advanced culture capabilities to generate …
Organ-on-chip (OOC) technology provides advanced culture capabilities to generate …
[HTML][HTML] Organs-on-chips technologies–A guide from disease models to opportunities for drug development
Current in-vitro 2D cultures and animal models present severe limitations in recapitulating
human physiopathology with striking discrepancies in estimating drug efficacy and side …
human physiopathology with striking discrepancies in estimating drug efficacy and side …
Advances in microfluidic blood–brain barrier (BBB) models
Therapeutic options for neurological disorders currently remain limited. The intrinsic
complexity of the brain architecture prevents potential therapeutics from reaching their …
complexity of the brain architecture prevents potential therapeutics from reaching their …
Microfluidic organ-on-a-chip system for disease modeling and drug development
Z Li, J Hui, P Yang, H Mao - Biosensors, 2022 - mdpi.com
An organ-on-a-chip is a device that combines micro-manufacturing and tissue engineering
to replicate the critical physiological environment and functions of the human organs …
to replicate the critical physiological environment and functions of the human organs …
Drug delivery across the blood–brain barrier: recent advances in the use of nanocarriers
The blood–brain barrier (BBB) has a significant contribution to homeostasis and protection
of the CNS. However, it also limits the crossing of therapeutics and thereby complicates the …
of the CNS. However, it also limits the crossing of therapeutics and thereby complicates the …
Integrating biosensors in organs-on-chip devices: A perspective on current strategies to monitor microphysiological systems
Organs-on-chip (OoC), often referred to as microphysiological systems (MPS), are advanced
in vitro tools able to replicate essential functions of human organs. Owing to their …
in vitro tools able to replicate essential functions of human organs. Owing to their …
Tailoring biomaterials for biomimetic organs-on-chips
Organs-on-chips are microengineered microfluidic living cell culture devices with
continuously perfused chambers penetrating to cells. By mimicking the biological features of …
continuously perfused chambers penetrating to cells. By mimicking the biological features of …
[HTML][HTML] Bio-functionalization of microfluidic platforms made of thermoplastic materials: A review
As a result of their favorable physical and chemical characteristics, thermoplastics have
garnered significant interest in the area of microfluidics. The moldable nature of these …
garnered significant interest in the area of microfluidics. The moldable nature of these …