The impressive development of cancer immunotherapy in the last few years originates from
a more precise understanding of control mechanisms in the immune system leading to the …

Immunotherapy constitutes a paradigm shift in cancer treatment. Its FDA approval for several
indications has yielded improved prognosis for cases where traditional therapy has shown …

Imaging of gene-expression patterns in live animals is difficult to achieve with fluorescent
proteins because tissues are opaque to visible light. Imaging of transgene expression with …

The use of molecular imaging technologies for brain imaging can not only play an important
supporting role in disease diagnosis and treatment but can also be used to deeply study …

At the beginning of the millennium, the first chemical exchange saturation transfer (CEST)
contrast agents were bio‐organic molecules. However, later, metal‐based CEST agents …

Superparamagnetic iron oxide (SPIO)‐labeling of cells has been applied for magnetic
resonance imaging (MRI) cell tracking for over 30 years, having resulted in a dozen or so …

MRI is a widely available clinical tool for cancer diagnosis and treatment monitoring. MRI
provides excellent soft tissue imaging, using a wide range of contrast mechanisms, and can …

Purpose Reporter gene imaging has been extensively used to longitudinally report on whole-
body distribution and viability of transplanted engineered cells. Multi-modal cell tracking can …

The ability to manipulate cellular function using an external stimulus is a powerful strategy
for studying complex biological phenomena. One approach to modulate the function of the …

Dynamic processes in host–guest systems, such as the exchange between bound and free
guests, can endow such systems with unique properties and function. However, both the …