Cancer associated-fibroblast-derived exosomes in cancer progression

C Li, AF Teixeira, HJ Zhu, P Ten Dijke - Molecular cancer, 2021 - Springer
To identify novel cancer therapies, the tumor microenvironment (TME) has received a lot of
attention in recent years in particular with the advent of clinical successes achieved by …

[HTML][HTML] Salivary biomarkers for oral squamous cell carcinoma diagnosis and follow-up: current status and perspectives

M Cristaldi, R Mauceri, O Di Fede, G Giuliana… - Frontiers in …, 2019 - frontiersin.org
Oral cancer is the sixth most common cancer type in the world, and 90% of it is represented
by oral squamous cell carcinoma (OSCC). Despite progress in preventive and therapeutic …

Breast cancer cell-derived extracellular vesicles promote CD8+ T cell exhaustion via TGF-β type II receptor signaling

F Xie, X Zhou, P Su, H Li, Y Tu, J Du, C Pan… - Nature …, 2022 - nature.com
Cancer immunotherapies have shown clinical success in various types of tumors but the
patient response rate is low, particularly in breast cancer. Here we report that malignant …

Molecular signature of subtypes of non-small-cell lung cancer by large-scale transcriptional profiling: identification of key modules and genes by weighted gene co …

M Niemira, F Collin, A Szalkowska, A Bielska… - Cancers, 2019 - mdpi.com
Non-small-cell lung cancer (NSCLC) represents a heterogeneous group of malignancies
consisting essentially of adenocarcinoma (ADC) and squamous cell carcinoma (SCC) …

Endosomal signalling via exosome surface TGFβ-1

GV Shelke, Y Yin, SC Jang, C Lässer… - Journal of …, 2019 - Taylor & Francis
Extracellular vesicles such as exosomes convey biological messages between cells, either
by surface-to-surface interaction or by shuttling of bioactive molecules to a recipient cell's …

A comprehensive picture of extracellular vesicles and their contents. Molecular transfer to cancer cells

A Jurj, O Zanoaga, C Braicu, V Lazar, C Tomuleasa… - Cancers, 2020 - mdpi.com
Critical processes such as growth, invasion, and metastasis of cancer cells are sustained via
bidirectional cell-to-cell communication in tissue complex environments. Such …

Proteomic insights into extracellular vesicle biology–defining exosomes and shed microvesicles

DW Greening, R Xu, SK Gopal, A Rai… - Expert review of …, 2017 - Taylor & Francis
ABSTRACT Introduction: Extracellular vesicles (EVs) are critical mediators of intercellular
communication, capable of regulating the transcriptional landscape of target cells through …

Impact of storage conditions on EV Integrity/Surface markers and cargos

A Sivanantham, Y Jin - Life, 2022 - mdpi.com
Extracellular vesicles (EVs) are small biological particles released into biofluids by every
cell. Based on their size, they are classified into small EVs (< 100 nm or< 200 nm) and …

The role of extracellular vesicles from different origin in the microenvironment of head and neck cancers

C Xie, N Ji, Z Tang, J Li, Q Chen - Molecular cancer, 2019 - Springer
The proliferation and metastasis ability of tumors are mediate by the" mutual dialogue"
between cells in the tumor microenvironment (TME). Extracellular vesicles (EVs), mainly …

Liquid biopsy in oral cancer

F Lousada-Fernandez, O Rapado-Gonzalez… - International journal of …, 2018 - mdpi.com
Oral cancer is one of the most prevalent forms of cancer worldwide. Carcinogenesis is a
complex process, in which heterogeneity plays an important role in the development and …