A review on the application and limitations of administrative health care data for the study of acute kidney injury epidemiology and outcomes in children

EH Ulrich, G So, M Zappitelli, R Chanchlani - Frontiers in Pediatrics, 2021 - frontiersin.org
Administrative health care databases contain valuable patient information generated by
health care encounters. These “big data” repositories have been increasingly used in …

“Is It Removed During Dialysis?”—Cognitive Dysfunction in Advanced Kidney Failure—A Review Article

K Crowe, TJ Quinn, PB Mark, MD Findlay - Frontiers in Neurology, 2021 - frontiersin.org
Cognitive impairment is independently associated with kidney disease and increases in
prevalence with declining kidney function. At the stage where kidney replacement therapy is …

Personalised cooler dialysate for patients receiving maintenance haemodialysis (MyTEMP): a pragmatic, cluster-randomised trial

AX Garg, AA Al-Jaishi, SN Dixon, JM Sontrop… - The Lancet, 2022 - thelancet.com
Background Haemodialysis centres have conventionally provided maintenance
haemodialysis using a standard dialysate temperature (eg, 36· 5° C) for all patients. Many …

Effectiveness of cold HD for the prevention of HD hypotension and mortality in the general HD population

C Zoccali, G Tripepi, L Neri, M Savoia… - Nephrology Dialysis …, 2023 - academic.oup.com
Background Cold hemodialysis (HD) prevented intradialysis hypotension (IDH) in small,
short-term, randomized trials in selected patients with IDH. Whether this treatments prevents …

Update on HD-Induced Multiorgan Ischemia: Brains and Beyond

CW McIntyre - Journal of the American Society of Nephrology, 2024 - journals.lww.com
Hemodialysis (HD) is a life-saving treatment for patients with kidney failure. However,
patients requiring HD have a 10-20 times higher risk of cardiovascular (CV) morbidity and …

Hyperhydration to Improve Kidney Outcomes in Children with Shiga Toxin-Producing E. coli Infection: a multinational embedded cluster crossover randomized trial …

SB Freedman, D Schnadower, M Estes, TC Casper… - Trials, 2023 - Springer
Background Shiga toxin-producing E. coli (STEC) infections affect children and adults
worldwide, and treatment remain solely supportive. Up to 15–20% of children infected by …

Cardiovascular safety of metoclopramide compared to domperidone: a population-based cohort study

A Cowan, AX Garg, E McArthur… - Journal of the …, 2021 - academic.oup.com
Background Metoclopramide and domperidone are common prokinetics used to alleviate
gastrointestinal symptoms. However, both drugs may trigger ventricular arrhythmias. Aim We …

Use cases of registry‐based randomized controlled trials—A review of the registries' contributions and constraints

N Kubesch, S Gaitonde, U Petriti… - Clinical and …, 2024 - Wiley Online Library
Registry‐based randomized controlled trials (RRCTs) can combine the advantages of
registries with those of randomization. This review aimed to expand the current knowledge …

[HTML][HTML] The Ottawa Statement implementation guidance document for cluster randomized trials in the hemodialysis setting

CE Goldstein, M Taljaard, SG Nicholls, M Beaucage… - Kidney International, 2024 - Elsevier
Research teams are increasingly interested in using cluster randomized trial (CRT) designs
to generate practice-guiding evidence for in-center maintenance hemodialysis. However …

Cultivating innovative pragmatic cluster-randomized registry trials embedded in hemodialysis care: workshop proceedings from 2018

EJ Lee, A Patel, RR Acedillo… - … Journal of Kidney …, 2019 - journals.sagepub.com
Hemodialysis is a life-sustaining treatment for persons with kidney failure. However, those
on hemodialysis still face a poor quality of life and a short life expectancy. High-quality …