Integrated proteogenomic characterization across major histological types of pituitary neuroendocrine tumors

F Zhang, Q Zhang, J Zhu, B Yao, C Ma, N Qiao, S He… - Cell Research, 2022 - nature.com
Pituitary neuroendocrine tumor (PitNET) is one of the most common intracranial tumors. Due
to its extensive tumor heterogeneity and the lack of high-quality tissues for biomarker …

[HTML][HTML] Therapeutic Exploitation of Neuroendocrine Transdifferentiation Drivers in Prostate Cancer

ZR Maylin, C Smith, A Classen, M Asim, H Pandha… - Cells, 2024 - mdpi.com
Neuroendocrine prostate cancer (NEPC), an aggressive and lethal subtype of prostate
cancer (PCa), often arises as a resistance mechanism in patients undergoing hormone …

[HTML][HTML] Targeted analysis of Ubiquitin-Specific Peptidase (USP8) in a population of Iranian people with Cushing's disease and a systematic review of the literature

N Hashemi-Madani, S Cheraghi, Z Emami… - BMC Endocrine …, 2024 - ncbi.nlm.nih.gov
Objective Activating mutation in Ubiquitin-specific peptidase (USP8) is identified to enhance
cell proliferation and adrenocorticotropic hormone (ACTH) secretion from corticotroph …

Neuromedin B receptor as a potential therapeutic target for corticotroph adenomas

T Sekizaki, H Kameda, A Nakamura, S Kuwabara… - Pituitary, 2023 - Springer
Purpose Cushing's disease (CD) results from autonomous adrenocorticotropic hormone
(ACTH) secretion by corticotroph adenomas, leading to excessive cortisol production …

Ubiquitination of ASCL1 mediates CD47 transcriptional activation of the AKT signaling pathway, and glycolysis promotes osteogenic differentiation of hBMSCs

J Zhang, L Zhu, J Zhou, Q Yu, G Yang, K Zhao… - In Vitro Cellular & …, 2023 - Springer
Bones are extremely dynamic organs that continually develop and remodel. This process
involves changes in numerous gene expressions. hBMSC cells can promote osteogenic …

[HTML][HTML] 垂体ACTH 瘤病理评估研究进展

计铭钰, 杨宇宏, 孙敏 - 南京医科大学学报(自然科学版), 2024 - jnmu.njmu.edu.cn
摘要分泌促肾上腺皮质激素(adrenocorticotropic hormone, ACTH) 的垂体腺瘤(垂体ACTH 瘤)
因过度分泌ACTH 刺激双侧肾上腺皮质增生而引起高皮质醇血症, 也称作库欣病(Cushing's …

[引用][C] Ubiquitination ofáASCL1 mediates CD47 transcriptional activation ofátheáAKT signaling pathway, andáglycolysis promotes osteogenic differentiation …

J KeáZhao5áĚ, C XumingáYang - In Vitro Cellular & Developmental Biology-Animal, 2023