Traditionally, the diagnosis of male infertility has relied upon microscopic assessment and
biochemical assays to determine human semen quality. The conventional parameters given …

This review summarizes the introduction of ICSI in the early 1990s as an assisted fertilization
procedure in couples with severe male factor infertility, who could not be helped by …

Background The effectiveness of in-vitro fertilisation (IVF) treatment depends both on the
overall success rate in the treating clinic and on the characteristics of the couple seeking …

The literature contains conflicting evidence regarding the existence of DNA damage in
spermatozoa from infertile male patients. To examine this phenomenon, we have studied …

In this study (May 1 until August 31, 1994) a total of 15 azoospermic patients suffering from
testicular failure were treated with a combination of testicular sperm extraction (TESE) and …

BACKGROUND: The integrity of sperm DNA is important for the success of natural or
assisted fertilization, as well as normal development of the embryo, fetus and child. ICSI, by …

STUDY QUESTION What is the semen quality of young adult men who were conceived 18–
22 years ago by ICSI for male infertility? SUMMARY ANSWER In this cohort of 54 young …

BACKGROUND: To evaluate the safety of ICSI, this study compared data of IVF and ICSI
children by collecting data on neonatal outcome and congenital malformations during …

BACKGROUND: IVF is limited by low success rates and an unacceptably high multiple
pregnancy rate. These outcomes would be improved significantly if a single embryo of high …

High success rates have been reported for the use of intracytoplasmic sperm injection (ICSI)
in alleviating essentially andrological infertility. However, neither the relationship between …