Studies on the parasite–host interaction may provide valuable information concerning the
modulation of molecular mechanisms as well as of the host immune system during infection …

This review tackles the concept of the evolutionary mismatch, in relation with the reduction of
the prevalence of the so-called “dirty old friends”. These formed the variegated community of …

Celastrol is an active compound extracted from the root bark of Triptergium wilfordii Hook F.,
also known as ̔Thunder of God Vine̓. It is a well-known Chinese medicinal herb that was …

Development of modern medicine and better living conditions in the 20th century helped in
reducing a number of cases of infectious diseases. During the same time, expansion of …

Poor cell survival and limited functional benefits have restricted mesenchymal stem cell
(MSC) efficacy for treating myocardial infarction (MI), suggesting that a better understanding …

The precise mechanism of the very effective therapeutic effect of gastrointestinal nematodes
on some autoimmune diseases is not clearly understood and is currently being intensively …

Parasitic helminths induce a transient, short-term inflammation at the beginning of infection,
but in persistent infection may suppress the systemic immune response by enhancing the …

Introduction Intestinal roundworms cause chronic debilitating disease in animals, including
humans. Traditional experimental models of these types of infection use a large single-dose …

In this manuscript, we explore the potential therapeutic use of helminths. After analyzing
helminths' role in connection with human health from the perspective of their symbiotic and …

Mast cells are essential immune cells involved in the host's defence against gastrointestinal
nematodes. To evade the immune response, parasitic nematodes produce a variety of …