The highly disagreeable sensation of pain results from an extraordinarily complex and
interactive series of mechanisms integrated at all levels of the neuroaxis, from the periphery …

IBM's Blue Gene supercomputer allows a quantum leap in the level of detail at which the
brain can be modelled. I argue that the time is right to begin assimilating the wealth of data …

Different brain rhythms, with both low-frequency and fast-frequency, are grouped within
complex wave-sequences. Instead of dissecting various frequency bands of the major …

During various states of vigilance, brain oscillations are grouped together through reciprocal
connections between the neocortex and thalamus. The coherent activity in corticothalamic …

Data from in vivo and in vitro experiments are discussed to emphasize that synaptic activities
in neocortex and thalamus have a decisive impact on intrinsic neuronal properties in intact …

We reviewed computer models that have been developed to reproduce and explain
epileptiform activity. Unlike other already-published reviews on computer models of …

Thalamic reticular neurons release the potent inhibitory neurotransmitter GABA and their
main targets are thalamocortical neurons in the dorsal thalamus. This article focuses on two …

To better understand population phenomena in thalamocortical neuronal ensembles, we
have constructed a preliminary network model with 3,560 multicompartment neurons …

It is currently believed that the mechanisms underlying spindle oscillations are related to
those that generate spike and wave (SW) discharges. The mechanisms of transition …

The objectives of this study were to evaluate the haemodynamic response of the cerebral
cortex and thalamus during generalized spike and wave or polyspike and wave (GSW) …