[HTML][HTML] Causes and consequences of snake venom variation
Snake venoms are mixtures of toxins that vary extensively between and within snake
species. This variability has serious consequences for the management of the world's 1.8 …
species. This variability has serious consequences for the management of the world's 1.8 …
[HTML][HTML] Multifunctional toxins in snake venoms and therapeutic implications: from pain to hemorrhage and necrosis
Animal venoms have evolved over millions of years for prey capture and defense from
predators and rivals. Snake venoms, in particular, have evolved a wide diversity of peptides …
predators and rivals. Snake venoms, in particular, have evolved a wide diversity of peptides …
[HTML][HTML] Snake venom metalloproteinases (SVMPs): a structure-function update
Snake venom metalloproteinases (SVMPs) represent a diverse group of multi-domain
proteins with several biological activities such as the ability to induce hemorrhage …
proteins with several biological activities such as the ability to induce hemorrhage …
A current perspective on snake venom composition and constituent protein families
T Tasoulis, GK Isbister - Archives of toxicology, 2023 - Springer
Snake venoms are heterogeneous mixtures of proteins and peptides used for prey
subjugation. With modern proteomics there has been a rapid expansion in our knowledge of …
subjugation. With modern proteomics there has been a rapid expansion in our knowledge of …
[HTML][HTML] Biogeographic venom variation in Russell's viper (Daboia russelii) and the preclinical inefficacy of antivenom therapy in snakebite hotspots
RR Senji Laxme, S Khochare, S Attarde… - PLoS neglected …, 2021 - journals.plos.org
Background Snakebite in India results in over 58,000 fatalities and a vast number of
morbidities annually. The majority of these clinically severe envenomings are attributed to …
morbidities annually. The majority of these clinically severe envenomings are attributed to …
[HTML][HTML] Biogeographical venom variation in the Indian spectacled cobra (Naja naja) underscores the pressing need for pan-India efficacious snakebite therapy
RR Senji Laxme, S Attarde, S Khochare… - PLOS neglected …, 2021 - journals.plos.org
Background Snake venom composition is dictated by various ecological and environmental
factors, and can exhibit dramatic variation across geographically disparate populations of …
factors, and can exhibit dramatic variation across geographically disparate populations of …
[HTML][HTML] Old World Vipers—a review about snake venom proteomics of Viperinae and their variations
Fine-tuned by millions of years of evolution, snake venoms have frightened but also
fascinated humanity and nowadays they constitute potential resources for drug …
fascinated humanity and nowadays they constitute potential resources for drug …
Vipers of Major clinical relevance in Europe: Taxonomy, venom composition, toxicology and clinical management of human bites
MR Di Nicola, A Pontara, GEN Kass, NI Kramer… - Toxicology, 2021 - Elsevier
Snakebites in Europe are mostly due to bites from Viperidae species of the genus Vipera.
This represents a neglected public health hazard with poorly defined incidence, morbidity …
This represents a neglected public health hazard with poorly defined incidence, morbidity …
The rise of genomics in snake venom research: recent advances and future perspectives
Snake venoms represent a danger to human health, but also a gold mine of bioactive
proteins that can be harnessed for drug discovery purposes. The evolution of snakes and …
proteins that can be harnessed for drug discovery purposes. The evolution of snakes and …
[HTML][HTML] Snake venom gland organoids
Wnt dependency and Lgr5 expression define multiple mammalian epithelial stem cell types.
Under defined growth factor conditions, such adult stem cells (ASCs) grow as 3D organoids …
Under defined growth factor conditions, such adult stem cells (ASCs) grow as 3D organoids …