The pathogenic basis of malaria
LH Miller, DI Baruch, K Marsh, OK Doumbo - Nature, 2002 - nature.com
Malaria is today a disease of poverty and underdeveloped countries. In Africa, mortality
remains high because there is limited access to treatment in the villages. We should follow …
remains high because there is limited access to treatment in the villages. We should follow …
Antigenic Variation in Plasmodium falciparum
The persistence of the human malaria parasite Plasmodium falciparum during blood stage
proliferation in its host depends on the successive expression of variant molecules at the …
proliferation in its host depends on the successive expression of variant molecules at the …
Computational improvements reveal great bacterial diversity and high metal toxicity in soil
J Gans, M Wolinsky, J Dunbar - Science, 2005 - science.org
The complexity of soil bacterial communities has thus far confounded effective
measurement. However, with improved analytical methods, we show that the abundance …
measurement. However, with improved analytical methods, we show that the abundance …
Single-cell RNA-seq reveals hidden transcriptional variation in malaria parasites
Single-cell RNA-sequencing is revolutionising our understanding of seemingly
homogeneous cell populations but has not yet been widely applied to single-celled …
homogeneous cell populations but has not yet been widely applied to single-celled …
Comparative genomics of the neglected human malaria parasite Plasmodium vivax
The human malaria parasite Plasmodium vivax is responsible for 25–40% of the∼ 515
million annual cases of malaria worldwide. Although seldom fatal, the parasite elicits severe …
million annual cases of malaria worldwide. Although seldom fatal, the parasite elicits severe …
Genome sequence and comparative analysis of the model rodent malaria parasite Plasmodium yoelii yoelii
Species of malaria parasite that infect rodents have long been used as models for malaria
disease research. Here we report the whole-genome shotgun sequence of one species …
disease research. Here we report the whole-genome shotgun sequence of one species …
Molecular aspects of severe malaria
Q Chen, M Schlichtherle… - Clinical microbiology …, 2000 - Am Soc Microbiol
Human infections with Plasmodium falciparum may result in severe forms of malaria. The
widespread and rapid development of drug resistance in P. falciparum and the resistance of …
widespread and rapid development of drug resistance in P. falciparum and the resistance of …
Reticulocyte-binding protein homologue 5–an essential adhesin involved in invasion of human erythrocytes by Plasmodium falciparum
Invasion of erythrocytes is a prerequisite in the life history of the malaria parasite. Members
of the reticulocyte-binding homologue family (PfRh) have been implicated in the invasion …
of the reticulocyte-binding homologue family (PfRh) have been implicated in the invasion …
The immunological balance between host and parasite in malaria
K Deroost, TT Pham, G Opdenakker… - FEMS microbiology …, 2016 - academic.oup.com
Coevolution of humans and malaria parasites has generated an intricate balance between
the immune system of the host and virulence factors of the parasite, equilibrating maximal …
the immune system of the host and virulence factors of the parasite, equilibrating maximal …
Molecular Mechanism for Switching of P. falciparum Invasion Pathways into Human Erythrocytes
J Stubbs, KM Simpson, T Triglia, D Plouffe, CJ Tonkin… - Science, 2005 - science.org
The malaria parasite, Plasmodium falciparum, exploits multiple ligand-receptor interactions,
called invasion pathways, to invade the host erythrocyte. Strains of P. falciparum vary in their …
called invasion pathways, to invade the host erythrocyte. Strains of P. falciparum vary in their …