Sleep plays a vital role in brain function and systemic physiology across many body
systems. Problems with sleep are widely prevalent and include deficits in quantity and …

Weight gain, obesity and diabetes have reached alarming levels in the developed world.
Traditional risk factors such as over‐eating, poor nutritional choices and lack of exercise …

OBJECTIVE: To develop comprehensive clinical practice guidelines for critically ill infants
and children, with specific attention to seven domains of care including pain …

The view that sleep is essential for survival is supported by the ubiquity of this behavior, the
apparent existence of sleep-like states in the earliest animals, and the fact that severe sleep …

Sleep deprivation is associated with considerable social, financial, and health-related costs,
in large measure because it produces impaired cognitive performance due to increasing …

Deficits in daytime performance due to sleep loss are experienced universally and
associated with a significant social, financial, and human cost. Microsleeps, sleep attacks …

Critically ill patients frequently experience poor sleep, characterized by frequent disruptions,
loss of circadian rhythms, and a paucity of time spent in restorative sleep stages. Factors that …

The energy allocation (EA) model defines behavioral strategies that optimize the temporal
utilization of energy to maximize reproductive success. This model proposes that all species …

Chronic sleep loss as a consequence of voluntary bedtime restriction is an endemic
condition in modern society. Although sleep exerts marked modulatory effects on glucose …

Background: Acute partial sleep deprivation increases plasma concentrations of ghrelin and
decreases those of leptin. Objective: The objective was to observe modifications in energy …