Current clinical landscape and global potential of bacteriophage therapy

NM Hitchcock, D Devequi Gomes Nunes, J Shiach… - Viruses, 2023 - mdpi.com
In response to the global spread of antimicrobial resistance, there is an increased demand
for novel and innovative antimicrobials. Bacteriophages have been known for their potential …

The Potential of Phage Therapy against the Emerging Opportunistic Pathogen Stenotrophomonas maltophilia

JG McCutcheon, JJ Dennis - Viruses, 2021 - mdpi.com
The isolation and characterization of bacteriophages for the treatment of infections caused
by the multidrug resistant pathogen Stenotrophomonas maltophilia is imperative as …

Phages to shape the gut microbiota?

S Dahlman, L Avellaneda-Franco, JJ Barr - Current Opinion in …, 2021 - Elsevier
Highlights•A diverse collection of bacteria and phages stably coexists within our gut.•Gut
dysbiosis seems to be marked by altered bacterial and phage composition.•Exogenous …

Deploying viruses against phytobacteria: Potential use of phage cocktails as a multifaceted approach to combat resistant bacterial plant pathogens

T Farooq, MD Hussain, MT Shakeel, M Tariqjaveed… - Viruses, 2022 - mdpi.com
Plants in nature are under the persistent intimidation of severe microbial diseases,
threatening a sustainable food production system. Plant-bacterial pathogens are a major …

A phage foundry framework to systematically develop viral countermeasures to combat antibiotic-resistant bacterial pathogens

VK Mutalik, AP Arkin - Iscience, 2022 - cell.com
At its current rate, the rise of antimicrobial-resistant (AMR) infections is predicted to paralyze
our industries and healthcare facilities while becoming the leading global cause of loss of …

Liposomal Delivery of Newly Identified Prophage Lysins in a Pseudomonas aeruginosa Model

D Morais, L Tanoeiro, AT Marques… - International Journal of …, 2022 - mdpi.com
Pseudomonas aeruginosa is a Gram-negative opportunistic bacterium that presents
resistance to several antibiotics, thus, representing a major threat to human and animal …

Speeding genomic island discovery through systematic design of reference database composition

SL Yu, CM Mageeney, F Shormin, N Ghaffari… - Plos one, 2024 - journals.plos.org
Background Genomic islands (GIs) are mobile genetic elements that integrate site-
specifically into bacterial chromosomes, bearing genes that affect phenotypes such as …

Precise microbiome engineering using natural and synthetic bacteriophages targeting an artificial bacterial consortium

T Tanaka, R Sugiyama, Y Sato, M Kawaguchi… - Frontiers in …, 2024 - frontiersin.org
In natural microbiomes, microorganisms interact with each other and exhibit diverse
functions. Microbiome engineering, which enables bacterial knockdown, is a promising …

Phytopathological management through bacteriophages: enhancing food security amidst climate change

I Ul Haq, M Khan, I Khan - Journal of Industrial Microbiology and …, 2024 - academic.oup.com
The increasing global population and climate change pose significant challenges to
agriculture, particularly in managing plant diseases caused by phytopathogens. Traditional …

Exploiting interbacterial antagonism for microbiome engineering

SS Yim, HH Wang - Current opinion in biomedical engineering, 2021 - Elsevier
Interbacterial antagonism can significantly impact microbiome assembly and stability and
can potentially be exploited to modulate microbes and microbial communities in diverse …