Human schistosomiasis

B Gryseels, K Polman, J Clerinx, L Kestens - The lancet, 2006 - thelancet.com
Schistosomiasis or bilharzia is a tropical disease caused by worms of the genus
Schistosoma. The transmission cycle requires contamination of surface water by excreta …

Schistosomiasis morbidity hotspots: roles of the human host, the parasite and their interface in the development of severe morbidity

PA Mawa, J Kincaid-Smith, EM Tukahebwa… - Frontiers in …, 2021 - frontiersin.org
Schistosomiasis is the second most important human parasitic disease in terms of
socioeconomic impact, causing great morbidity and mortality, predominantly across the …

Ecological rules governing helminth–microparasite coinfection

AL Graham - Proceedings of the National Academy of …, 2008 - National Acad Sciences
Coinfection of a host by multiple parasite species has important epidemiological and clinical
implications. However, the direction and magnitude of effects vary considerably among …

Epidemiology and control of human schistosomiasis in Tanzania

HD Mazigo, F Nuwaha, SM Kinung'hi, D Morona… - Parasites & vectors, 2012 - Springer
In Tanzania, the first cases of schistosomiasis were reported in the early 19th century. Since
then, various studies have reported prevalences of up to 100% in some areas. However, for …

The health impact of polyparasitism in humans: are we under-estimating the burden of parasitic diseases?

R Pullan, S Brooker - Parasitology, 2008 - cambridge.org
Parasitic infections are widespread throughout the tropics and sub-tropics, and infection with
multiple parasite species is the norm rather than the exception. Despite the ubiquity of …

Co‐infection of helminths and malaria: modulation of the immune responses to malaria

FC Hartgers, M Yazdanbakhsh - Parasite immunology, 2006 - Wiley Online Library
Chronic helminth infections induce strong type 2 and regulatory immune responses and are
known to influence immune activity to other antigens such as allergens and vaccines. Since …

Malaria and helminth interactions in humans: an epidemiological viewpoint

TW Mwangi, JM Bethony, S Brooker - Annals of Tropical Medicine …, 2006 - Taylor & Francis
In the tropics, helminths are among the most common chronic infections of humans and
Plasmodium infections the most deadly. As these two groups of parasites have similar …

Regulating immunity to malaria

EM Riley, S Wahl, DJ Perkins… - Parasite immunology, 2006 - Wiley Online Library
The optimal outcome of a malaria infection is that parasitized cells are killed and degraded
without inducing significant pathology. Since much of the pathology of malaria infection can …

Spatial epidemiology of human schistosomiasis in Africa: risk models, transmission dynamics and control

S Brooker - Transactions of the Royal Society of Tropical …, 2007 - academic.oup.com
This paper reviews recent studies on the spatial epidemiology of human schistosomiasis in
Africa. The integrated use of geographical information systems, remote sensing and …

Recent approaches to chemical discovery and development against malaria and the neglected tropical diseases human African trypanosomiasis and schistosomiasis

M Njoroge, NM Njuguna, P Mutai… - Chemical …, 2014 - ACS Publications
Neglected tropical diseases (NTDs) refer to a group of infectious diseases, which though
treatable and/or preventable, remain a leading cause of morbidity and mortality among the …