First cases that point at a correlation between SARS-CoV-2 infections and the development
of Parkinson's disease (PD) have been reported. Currently, it is unclear if there is also a …

The past few years have resulted in an increased awareness and recognition of the
prevalence and roles of intrinsically disordered proteins and protein regions (IDPs and IDRs …

Abstract α-Synuclein (αS) is a presynaptic disordered protein whose aberrant aggregation is
associated with Parkinson's disease. The functional role of αS is still debated, although it …

Peripheral membrane proteins associate reversibly with biological membranes that,
compared to protein binding partners, are structurally labile and devoid of specific binding …

Alpha synuclein (a-syn) is an intrinsically disordered protein prevalent in neurons, and
aggregated forms are associated with synucleinopathies including Parkinson's disease …

Amyloid fibrils of the protein α-synuclein (αS) have recently been identified as a biomarker
for Parkinson's disease (PD). To detect the presence of these amyloid fibrils, seed …

Clathrin-mediated endocytosis depends on the formation of functional clathrin-coated pits
that recruit cargos and mediate the uptake of those cargos into the cell. However, it remains …

Theoretical concepts from polymer physics are often used to describe intrinsically
disordered proteins (IDPs). However, amino acid interactions within and between regions of …

The aberrant aggregation of α-Synuclein (αS), a disordered protein primarily localised at the
neuronal synapses, is associated with a number of neurodegenerative disorders including …

Alpha-synuclein (αS) is an intrinsically disordered protein (IDP) that is abundantly present in
the brain and is associated with Parkinson's disease (PD). In spite of its abundance and its …