Effect of estrous cycle on behavior of females in rodent tests of anxiety
TA Lovick, H Zangrossi Jr - Frontiers in psychiatry, 2021 - frontiersin.org
Anxiety disorders are more prevalent in women than in men. In women the menstrual cycle
introduces another variable; indeed, some conditions eg, premenstrual syndrome, are …
introduces another variable; indeed, some conditions eg, premenstrual syndrome, are …
Estrous cycle mediates midbrain neuron excitability altering social behavior upon stress
MR Shanley, Y Miura, CA Guevara… - Journal of …, 2023 - Soc Neuroscience
The estrous cycle is a potent modulator of neuron physiology. In rodents, in vivo ventral
tegmental area (VTA) dopamine (DA) activity has been shown to fluctuate across the estrous …
tegmental area (VTA) dopamine (DA) activity has been shown to fluctuate across the estrous …
Dicer ablation in Kiss1 neurons impairs puberty and fertility preferentially in female mice
J Roa, M Ruiz-Cruz, F Ruiz-Pino, R Onieva… - Nature …, 2022 - nature.com
Kiss1 neurons, producing kisspeptins, are essential for puberty and fertility, but their
molecular regulatory mechanisms remain unfolded. Here, we report that congenital ablation …
molecular regulatory mechanisms remain unfolded. Here, we report that congenital ablation …
Seizure burden fluctuates with the female reproductive cycle in a mouse model of chronic temporal lobe epilepsy
J Li, LK Leverton, LM Naganatanahalli… - Experimental …, 2020 - Elsevier
Women with catamenial epilepsy often experience increased seizure burden near the time
of ovulation (periovulatory) or menstruation (perimenstrual). To date, a rodent model of …
of ovulation (periovulatory) or menstruation (perimenstrual). To date, a rodent model of …
Phenotypic differences based on lateralization of intrahippocampal kainic acid injection in female mice
Clinical evidence indicates that patients with temporal lobe epilepsy (TLE) often show
differential outcomes of comorbid conditions in relation to the lateralization of the seizure …
differential outcomes of comorbid conditions in relation to the lateralization of the seizure …
Multi-organ transcriptome atlas of a mouse model of relative energy deficiency in sport
L van Rosmalen, J Zhu, G Maier, EG Gacasan, T Lin… - Cell metabolism, 2024 - cell.com
Insufficient energy intake to meet energy expenditure demands of physical activity can result
in systemic neuroendocrine and metabolic abnormalities in activity-dependent anorexia and …
in systemic neuroendocrine and metabolic abnormalities in activity-dependent anorexia and …
Automated classification of estrous stage in rodents using deep learning
The rodent estrous cycle modulates a range of biological functions, from gene expression to
behavior. The cycle is typically divided into four stages, each characterized by distinct …
behavior. The cycle is typically divided into four stages, each characterized by distinct …
[HTML][HTML] Low dose exposure to dioxins alters hepatic energy metabolism and steatotic liver disease development in a sex-specific manner
OE Bolatimi, Y Hua, FA Ekuban, TC Gripshover… - Environment …, 2024 - Elsevier
Abstract “Dioxins” are persistent organic pollutants (POPs) that are continuously present in
the environment at appreciable levels and have been associated with increased risk of …
the environment at appreciable levels and have been associated with increased risk of …
[HTML][HTML] Increased GABA transmission to GnRH neurons after intrahippocampal kainic acid injection in mice is sex-specific and associated with estrous cycle …
RJ Ingram, LK Leverton, VC Daniels, J Li… - Neurobiology of …, 2022 - Elsevier
Patients with epilepsy develop reproductive endocrine comorbidities at a rate higher than
that of the general population. Clinical studies have identified disrupted luteinizing hormone …
that of the general population. Clinical studies have identified disrupted luteinizing hormone …
Sex and estrous cycle stage shape left-right asymmetry in chronic hippocampal seizures in mice
CA Cutia, LK Leverton, CA Christian-Hinman - Eneuro, 2023 - eneuro.org
Lateralization of hippocampal function is indicated by varied outcomes of patients with
neurologic disorders that selectively affect one hemisphere of this structure, such as …
neurologic disorders that selectively affect one hemisphere of this structure, such as …