A significant body of evidence supports the protective role of exercise training (ET) in
cardiovascular diseases, skeletal muscle dystrophies, several types of cancer, Alzheimer …

A significant proportion of mammalian genomes corresponds to genes that transcribe long
non-coding RNAs (lncRNAs). Throughout the last decade, the number of studies concerning …

Emerging evidences suggest that necrosis is programmed and is one of the main forms of
cell death in the pathological process in cardiac diseases. Long noncoding RNAs (lncRNAs) …

Abstract Background Long noncoding RNAs (lncRNAs) are non-protein coding transcripts
regulating a variety of physiological and pathological functions. However, their implication in …

Transforming growth factor β (TGF-β)/Smad3 signaling plays a role in tissue fibrosis. We
report here that Erbb4-IR is a novel long non-coding RNA (lncRNA) responsible for TGF …

Vascular remodelling is a multifactorial process that involves both adaptive and maladaptive
changes of the vessel wall through, among others, cell proliferation and migration, but also …

Background: We generated a rat model of diabetic cardiomyopathy (DCM) and reported
significant upregulation of the long non-coding RNA DCRF. This study was designed to …

Background Cardiac fibrosis is a leading cause of cardiac dysfunction in patients with
diabetes. However, the underlying mechanisms of cardiac fibrosis remain unclear. This …

Background/Aims: The expression of a novel lncRNA, myocardial infarction associated
transcript 1 (Mirt1), has been shown to be upregulated in acute myocardial infarction (AMI) …

BACKGROUND: Cardiac fibroblasts have crucial roles in the heart. In particular, fibroblasts
differentiate into myofibroblasts in the damaged myocardium, contributing to scar formation …