Current medication for anxiety disorders is suboptimal in terms of efficiency and tolerability,
highlighting the need for improved drug treatments. In this review an overview of drugs …

Humans are an unusually prosocial species, who engage in social behaviors that include
altruism—whereby an individual engages in costly or risky acts to improve the welfare of …

The release of dopamine (DA) regulates rewarding behavior and motor actions through
striatum-targeting efferents from ventral tegmental area (VTA) and substantia nigra pars …

Oxytocin (OXT) is a neuropeptide which has a critical role in human social behaviour and
cognition. Research investigating the role of OXT on functional brain changes in humans …

Could nose-to-brain pathways mediate the effects of peptides such as oxytocin (OT) on brain
physiology when delivered intranasally? We address this question by contrasting two …

Social dysfunction is a core symptom of many psychiatric disorders and current medications
have little or no remedial effects on this. Following on from extensive studies on animal …

In recent years ample studies have reported that intranasal administration of the
neuropeptide oxytocin can facilitate social motivation and cognition in healthy and clinical …

Oxytocin neurones in the hypothalamus are activated by stressful stimuli and food intake.
The oxytocin receptor is located in various brain regions, including the sensory information …

Humans exhibit considerable variation in how they value their own interest relative to the
interests of others. Deciphering the neural codes representing potential rewards for self and …

Acute and chronic administration of intranasal oxytocin and vasopressin have been
extensively utilized in both animal models and human preclinical and clinical studies over …