The role of nitric oxide on endothelial function

D Tousoulis, AM Kampoli… - Current vascular …, 2012 - ingentaconnect.com
The vascular endothelium is a monolayer of cells between the vessel lumen and the
vascular smooth muscle cells. Nitric oxide (NO) is a soluble gas continuously synthesized …

Nitric oxide as a signaling molecule in the vascular system: an overview

LJ Ignarro, G Cirino, A Casini… - Journal of cardiovascular …, 1999 - journals.lww.com
In retrospect, basic research in the fields of nitric oxide (NO) and cyclic guanosine
monophosphate (cGMP) during the past two decades appears to have followed a logical …

Copper complexes of non-steroidal anti-inflammatory drugs: an opportunity yet to be realized

JE Weder, CT Dillon, TW Hambley, BJ Kennedy… - Coordination Chemistry …, 2002 - Elsevier
The proposed curative properties of Cu-based non-steroidal anti-inflammatory drugs
(NSAIDs) have led to the development of numerous Cu (II) complexes of NSAIDs with …

Nitric oxide in mucosal defense: a little goes a long way

JL Wallace, MJS Miller - Gastroenterology, 2000 - Elsevier
Nitric oxide (NO) is now recognized as an important modulator of an enormous number of
physiological processes, ranging from blood pressure regulation to neuronal transmission to …

Nitric oxide in gastrointestinal health and disease

V Shah, G Lyford, G Gores, G Farrugia - Gastroenterology, 2004 - Elsevier
Nitric oxide is an intracellular and intercellular messenger with important functions in a
number of physiologic and pathobiologic processes within gastroenterology and …

Role of the arginine-nitric oxide pathway in the regulation of vascular smooth muscle cell proliferation

LJ Ignarro, GM Buga, LH Wei… - Proceedings of the …, 2001 - National Acad Sciences
The objective of this study was to elucidate the mechanisms by which nitric oxide (NO)
inhibits rat aortic smooth muscle cell (RASMC) proliferation. Two products of the arginine …

[HTML][HTML] Role of prostaglandins in gastroprotection and gastric adaptation

T Brzozowski, PC Konturek, SJ Konturek… - Journal of physiology …, 2005 - jpp.krakow.pl
Since Robert discovery that pretreatment with prostaglandin (PG) applied in non-
antisecretory dose can prevent the injury of gastric mucosa induced by necrotizing agents …

Current perspectives in NSAID‐induced gastropathy

M Sinha, L Gautam, PK Shukla, P Kaur… - Mediators of …, 2013 - Wiley Online Library
Nonsteroidal anti‐inflammatory drugs (NSAIDs) are the most highly prescribed drugs in the
world. Their analgesic, anti‐inflammatory, and antipyretic actions may be beneficial; …

Gastrointestinal effects of nonsteroidal anti‐inflammatory drugs

BJR Whittle - Fundamental & clinical pharmacology, 2003 - Wiley Online Library
Non‐steroidal anti‐inflammatory drugs (NSAIDs) causes extensive damage to the
gastrointestinal (GI) tract. The underlying mechanisms of gastric injury include topical irritant …

Nitric oxide–releasing drugs

C Napoli, LJ Ignarro - Annual review of pharmacology and …, 2003 - annualreviews.org
Pharmacological compounds that release nitric oxide (NO) have been useful tools for
evaluating the broad role of NO in physiology and therapeutics. NO deficiency has been …