Sex-biased gene expression at single-cell resolution: cause and consequence of sexual dimorphism

I Darolti, JE Mank - Evolution Letters, 2023 - academic.oup.com
Gene expression differences between males and females are thought to be key for the
evolution of sexual dimorphism, and sex-biased genes are often used to study the molecular …

The Appropriateness of Medical Devices Is Strongly Influenced by Sex and Gender

I Campesi, F Franconi, PA Serra - Life, 2024 - mdpi.com
Until now, research has been performed mainly in men, with a low recruitment of women;
consequentially, biological, physiological, and physio-pathological mechanisms are less …

Transcriptomics, metabolomics, and in-silico drug predictions for liver damage in young and aged burn victims

B Malachowska, WL Yang, A Qualman, I Muro… - Communications …, 2023 - nature.com
Burn induces a systemic response affecting multiple organs, including the liver. Since the
liver plays a critical role in metabolic, inflammatory, and immune events, a patient with …

Human-Induced Pluripotent Stem Cell–Based Models for Studying Sex-Specific Differences in Neurodegenerative Diseases

E Kiris - Cell Biology and Translational Medicine, Volume 16 …, 2021 - Springer
The prevalence of neurodegenerative diseases is steadily increasing worldwide, and
epidemiological studies strongly suggest that many of the diseases are sex-biased. It has …

Adipose Tissue-Derived Mesenchymal Stem Cells Extend the Lifespan and Enhance Liver Function in Hepatocyte Organoids

SA Ock, SY Kim, WS Ju, YI Kim, HY Wi… - International Journal of …, 2023 - mdpi.com
In this study, we generated hepatocyte organoids (HOs) using frozen-thawed primary
hepatocytes (PHs) within a three-dimensional (3D) Matrigel dome culture in a porcine …

Effect of Serum and Oxygen on the In Vitro Culture of Hanwoo Korean Native Cattle-Derived Skeletal Myogenic Cells Used in Cellular Agriculture

SA Ock, KM Seo, WS Ju, YI Kim, HY Wi, P Lee - Foods, 2023 - mdpi.com
Skeletal muscle-derived myogenic cells (SKMCs) are novel protein sources capable of
replacing animal meat. However, SKMCs have not been commercialized owing to poor …