Unveiling the connection: long-chain non-coding RNAs and critical signaling pathways in breast cancer

R Thapa, O Afzal, G Gupta, AA Bhat, WH Almalki… - … -Research and Practice, 2023 - Elsevier
Breast cancer is a complex and diverse condition that disrupts multiple signaling pathways
essential for cell proliferation, survival, and differentiation. Recently, the significant …

A comprehensive review on the emerging role of long non-coding RNAs in the regulation of NF-κB signaling in inflammatory lung diseases

AA Bhat, O Afzal, N Agrawal, R Thapa… - International journal of …, 2023 - Elsevier
Public health globally faces significant risks from conditions like acute respiratory distress
syndrome (ARDS), chronic obstructive pulmonary disease (COPD), and various …

Targeting the PI3K/AKT/mTOR signaling pathway in the treatment of human diseases: Current status, trends, and solutions

J Huang, L Chen, J Wu, D Ai, JQ Zhang… - Journal of medicinal …, 2022 - ACS Publications
The phosphoinositide 3-kinase (PI3K)/protein kinase B (AKT)/mammalian target of
rapamycin (mTOR) pathway is one of the most important intracellular pathways involved in …

Long non-coding RNA mediated drug resistance in breast cancer

D Singh, YG Assaraf, RN Gacche - Drug Resistance Updates, 2022 - Elsevier
Breast cancer is one of the most prevalent cancers in women and a leading cause of
mortality. As per the GLOBCAN report of 2021, breast cancer has surpassed lung cancer …

Interactome battling of lncRNA CCDC144NL-AS1: Its role in the emergence and ferocity of cancer and beyond

YK Abd El Fattah, AI Abulsoud, SG AbdelHamid… - International Journal of …, 2022 - Elsevier
Long non-coding RNAs (lncRNAs) were, once, viewed as “noise” for transcription. Recently,
many lncRNAs are functionally linked to several human disorders, including cancer. Coiled …

Modulating epigenetic modifications for cancer therapy

LJ Castro-Muñoz, E Vázquez Ulloa… - Oncology …, 2023 - spandidos-publications.com
Cancer is a global public health concern. Alterations in epigenetic processes are among the
earliest genomic aberrations occurring during cancer development and are closely related …

Interplay between LncRNAs and microRNAs in breast cancer

H Schwarzenbach, PB Gahan - International journal of molecular …, 2023 - mdpi.com
(1) Although long noncoding RNAs (lncRNAs) are known to be precursors of microRNAs
(miRNAs), they frequently act as competing endogoneous RNAs (ceRNAs), yet still their …

Epigenetic regulation in breast cancer: Insights on epidrugs

A Kim, K Mo, H Kwon, S Choe, M Park, W Kwak… - Epigenomes, 2023 - mdpi.com
Breast cancer remains a common cause of cancer-related death in women. Therefore,
further studies are necessary for the comprehension of breast cancer and the revolution of …

Long noncoding RNAs in the pathogenesis of insulin resistance

W Yang, Y Lyu, R Xiang, J Yang - International journal of molecular …, 2022 - mdpi.com
Insulin resistance (IR), designated as the blunted response of insulin target tissues to
physiological level of insulin, plays crucial roles in the development and progression of …

The cross-talk between LncRNAs and JAK-STAT signaling pathway in cancer

A Hjazi, RF Obaid, SS Ali, B Abdullaev… - … -Research and Practice, 2023 - Elsevier
Long non-coding RNAs (lncRNAs) are non-coding RNAs that were transcribed from the
human genome and have become important regulators in a number of cellular activities …