2000 Fleming Lecture. The origin and evolution of hepatitis viruses in humans
P Simmonds - Journal of General Virology, 2001 - microbiologyresearch.org
The spread and origins of hepatitis C virus (HCV) in human populations have been the
subject of extensive investigations, not least because of the importance this information …
subject of extensive investigations, not least because of the importance this information …
Virus 'quasispecies': making a mountain out of a molehill?
DB Smith, J McAllister, C Casino… - Journal of General …, 1997 - microbiologyresearch.org
The study of virus variation covers a wide range of phenomena. At one extreme are the
comprehensive differences that allow viruses to be arranged taxonomically into different …
comprehensive differences that allow viruses to be arranged taxonomically into different …
Classification, nomenclature, and database development for hepatitis C virus (HCV) and related viruses: proposals for standardization
This paper presents a summary of the recommendations that were formulated for the
purposes of unifying the nomenclature for hepatitis C virus (HCV), based upon guidelines of …
purposes of unifying the nomenclature for hepatitis C virus (HCV), based upon guidelines of …
Conserved RNA secondary structures in Flaviviridae genomes
C Thurner, C Witwer, IL Hofacker… - Journal of General …, 2004 - microbiologyresearch.org
Presented here is a comprehensive computational survey of evolutionarily conserved
secondary structure motifs in the genomic RNAs of the family Flaviviridae. This virus family …
secondary structure motifs in the genomic RNAs of the family Flaviviridae. This virus family …
High incidence of hepatitis B infections among chronic hepatitis cases of unknown aetiology
I Chemin, F Zoulim, P Merle, A Arkhis, M Chevallier… - Journal of …, 2001 - Elsevier
Background/Aims: In approximately 5% of chronic liver disease cases, no aetiology can be
identified. We selected sera from 50 patients with chronic hepatitis of unknown aetiology …
identified. We selected sera from 50 patients with chronic hepatitis of unknown aetiology …
Structural constraints on RNA virus evolution
P Simmonds, DB Smith - Journal of virology, 1999 - Am Soc Microbiol
The recently discovered hepatitis G virus (HGV) or GB virus C (GBV-C) is widely distributed
in human populations, and homologues such as HGV/GBV-CCPZ and GBV-A are found in a …
in human populations, and homologues such as HGV/GBV-CCPZ and GBV-A are found in a …
Reconstructing the origins of human hepatitis viruses
P Simmonds - … Transactions of the Royal Society of …, 2001 - royalsocietypublishing.org
Infections with hepatitis B and C viruses (HBV, HCV) are widespread in human populations
throughout the world, and are major causes of chronic liver disease and liver cancer. HBV …
throughout the world, and are major causes of chronic liver disease and liver cancer. HBV …
[HTML][HTML] GB virus type C/hepatitis G virus: a non-pathogenic flavivirus associated with prolonged survival in HIV-infected individuals
PM Polgreen, J Xiang, Q Chang, JT Stapleton - Microbes and infection, 2003 - Elsevier
GB virus C (GBV-C) is a common virus that does not appear to cause disease. GBV-C
persists in up to 50% of exposed individuals, and virus replication appears to be in …
persists in up to 50% of exposed individuals, and virus replication appears to be in …
Phylogenetic analysis of GBV-C/hepatitis G virus
Comparison of 33 epidemiologically distinct GBV-C/hepatitis G virus complete genome
sequences suggests the existence of four major phylogenetic groupings that are equally …
sequences suggests the existence of four major phylogenetic groupings that are equally …
Role of GB virus C in modulating HIV disease
C Schwarze-Zander, JT Blackard… - Expert review of anti …, 2012 - Taylor & Francis
GB virus C (GBV-C) is a member of the Flaviviridae family and the most closely related
human virus to HCV. However, GBV-C does not replicate in hepatocytes, but rather in …
human virus to HCV. However, GBV-C does not replicate in hepatocytes, but rather in …