Antimicrobial resistance constitutes one of the major challenges facing humanity in the
Twenty-First century. The spread of resistant pathogens has been such that the possibility of …

Background is provided on biofilms, including their formation, tolerance mechanisms,
structure, and morphology within the context of chronic wounds. The features of biofilms in …

Biofilms are ubiquitous communities of tightly associated bacteria encased in an
extracellular matrix. Bacillus subtilis has long served as a robust model organism to examine …

It has long been axiomatic that a protein's structure determines its function. Intrinsically
disordered proteins (IDPs) and disordered protein regions (IDRs) defy this structure …

A number of bacterial cell processes are confined functional membrane microdomains
(FMMs), structurally and functionally similar to lipid rafts of eukaryotic cells. How bacteria …

The bacterial cytoplasmic membrane is composed of roughly equal proportions of lipids and
proteins. The main lipid components are phospholipids, which vary in acyl chain length …

Planctomycetes form a distinct phylum of the domain Bacteria and possess unusual features
such as intracellular compartmentalization and a lack of peptidoglycan in their cell walls …

Short antimicrobial peptides rich in arginine (R) and tryptophan (W) interact with
membranes. To learn how this interaction leads to bacterial death, we characterized the …

The functionality of cellular membranes relies on the molecular order imparted by lipids. In
eukaryotes, sterols such as cholesterol modulate membrane order, yet they are not typically …

Multi-species biofilm communities are environments in which complex but ill understood
exchanges between bacteria occur. Although monospecies cultures are still widely used in …