Supercritical fluid chromatography as a tool for enantioselective separation; a review

K Kalíková, T Šlechtová, J Vozka, E Tesařová - Analytica Chimica Acta, 2014 - Elsevier
Supercritical fluid chromatography (SFC) has become popular in the field of enantioselective
separations. Many works have been reported during the last years. This review covers the …

Enantioselective separations with supercritical fluids-review

C West - Current analytical chemistry, 2014 - ingentaconnect.com
This paper presents a review of the literature covering separations of enantiomers achieved
with supercritical fluids. Supercritical fluid chromatography (SFC) is the main technique …

Chiral resolution of (±)-flurbiprofen using molecularly imprinted hydrazidine-modified cellulose microparticles

HS AlSalem, M Monier, MA Abomuti… - International Journal of …, 2023 - Elsevier
Flurbiprofen (FP) is one of the non-steroidal anti-inflammatory drugs (NSAIDs) commonly
used to treat arthritic conditions. FP has two enantiomers: S-FP and R-FP. S-FP has potent …

Recent advances in pharmaceutical separations with supercritical fluid chromatography using chiral stationary phases

W Ren-Qi, O Teng-Teng, N Siu-Choon… - TrAC Trends in Analytical …, 2012 - Elsevier
Supercritical fluid chromatography (SFC) has developed rapidly in recent years, particularly
in the area of enantioseparations. The merits of SFC (eg, fast analysis speed, wide polarity …

Recent progress of enantioseparation under scale production (2014–2019)

D Wu, F Pan, W Tan, L Gao, Y Tao… - Journal of separation …, 2020 - Wiley Online Library
Very different from enantiorecognition at an analytical level, preparative enantioseparation
at scale production has to confront many problems. In recent years, various separation …

Design of preparative-supercritical fluid chromatography

A Rajendran - Journal of Chromatography A, 2012 - Elsevier
Preparative supercritical fluid chromatography (prep-SFC) is an important separation
process in the chromatographers toolbox. Owing to the unique properties of the mobile …

Peak distortions arising from large-volume injections in supercritical fluid chromatography

Y Dai, G Li, A Rajendran - Journal of Chromatography A, 2015 - Elsevier
Preparative separations in supercritical fluid chromatography (SFC) involve the injection of
large volumes of the solute. In SFC, the mobile phase is typically high pressure CO 2+ …

Enantioseparation of racemic flurbiprofen by aqueous two‐phase extraction with binary chiral selectors of L‐dioctyl tartrate and L‐tryptophan

Z Chen, W Zhang, L Wang, H Fan, Q Wan, X Wu… - Chirality, 2015 - Wiley Online Library
A novel method for chiral separation of flurbiprofen enantiomers was developed using
aqueous two‐phase extraction (ATPE) coupled with biphasic recognition chiral extraction …

Investigation of Isoprostanes as Potential Biomarkers for Alzheimer's Disease Using Chiral LC-MS/MS and SFC-MS/MS

V Goss, A Cazenave-Gassiot… - Current Analytical …, 2014 - ingentaconnect.com
Alzheimer's disease (AD) is a progressive neurodegenerative disorder that must be
diagnosed early to increase drug therapy efficacy. No early definitive diagnostic tool …

Optimization of an improved single-column chromatographic process for the separation of enantiomers

MK Kazi, B Medi, M Amanullah - Journal of Chromatography A, 2012 - Elsevier
This work addresses optimization of an improved single-column chromatographic (ISCC)
process for the separation of guaifenesin enantiomers. Conventional feed injection and …