Neurotransmitters are conventionally viewed as nerve-secreted substances that mediate the
stimulatory or inhibitory neuronal functions through binding to their respective receptors. In …

The most frequently mutated metabolic genes in human cancer are those encoding the
enzymes isocitrate dehydrogenase 1 (IDH1) and IDH2; these mutations have so far been …

Simple Summary The most prevalent and lethal primary brain tumor, glioblastoma
multiforme (GBM), exhibits fast growth and widespread invasion and has a poor prognosis …

Succinic semialdehyde dehydrogenase deficiency (SSADHD) is a rare genetic disorder
caused by inefficient metabolic breakdown of the major inhibitory neurotransmitter, γ …

Abstract Introduction Aldehyde dehydrogenase 1A3 (ALDH1A3) is a cancer stem cell (CSC)
marker and in breast cancer it is associated with triple-negative/basal-like subtypes and …

Synaptic transmission is closely linked to brain energy and neurotransmitter metabolism.
However, the extent of brain metabolism of the inhibitory neurotransmitter γ‐aminobutyric …

Ligand-gated ion channels are an ionotropic receptor subtype characterized by the binding
of an extracellular ligand, followed by the transient passage of ions through a …

Simple Summary Aiming to discover potential treatments for GBM, this review connects
emerging research on the roles of neurotransmitters in the normal neural and the GBM …

Pancreatic cancer (PC) is a highly lethal malignancy with a 5-year survival rate of less than
8%. The fate of PC is determined not only by the malignant behavior of the cancer cells, but …

One important feature of tumour development is the regulatory role of metabolic plasticity in
maintaining the balance of mitochondrial oxidative phosphorylation and glycolysis in cancer …