Parietal cells are responsible for gastric acid secretion, which aids in the digestion of food,
absorption of minerals, and control of harmful bacteria. However, a fine balance of activators …

The absorption of glucose is electrogenic in the small intestinal epithelium. The major route
for the transport of dietary glucose from intestinal lumen into enterocytes is the Na+/glucose …

Renal salt loss in Bartter's syndrome is caused by impaired transepithelial transport in the
loop of Henle. Sodium chloride is taken up apically by the combined activity of NKCC2 (Na+ …

For over 150 years Australia has exported bulk, undifferentiated, commodities such as wool,
wheat, meat and sugar to the UK and more recently to Japan, Korea, and the Middle East. It …

Since the first discovery of Kvβ-subunits more than 15 years ago, many more ancillary Kv
channel subunits were characterized, for example, KChIPs, KCNEs, and BKβ-subunits. The …

The voltage-gated KCNQ1 (KvLQT1, Kv7. 1) potassium channel plays a crucial role in
shaping the cardiac action potential as well as in controlling the water and salt homeostasis …

Calcium balance is essential for a multitude of physiological processes, ranging from cell
signaling to maintenance of bone health. Adequate intestinal absorption of calcium is a …

Voltage-gated potassium (Kv) channels mediate rapid, selective diffusion of K+ ions through
the plasma membrane, controlling cell excitability, secretion and signal transduction. KCNE …

Kv7 channels are voltage-gated potassium channels encoded by KCNQ genes that have a
considerable physiological impact in many cell types. This reliance upon Kv7 channels for …

Current therapies to treat gastroesophageal reflux disease (GERD), peptic ulcer disease
(PUD), and other acid-related diseases either prevent stimulation of the parietal cell (H2 …