The principles, design and applications of fused-ring electron acceptors

J Wang, P Xue, Y Jiang, Y Huo, X Zhan - Nature Reviews Chemistry, 2022 - nature.com
Fused-ring electron acceptors (FREAs) have a donor–acceptor–donor structure comprising
an electron-donating fused-ring core, electron-accepting end groups, π-bridges and side …

Aggregation-induced emission (AIE), life and health

H Wang, Q Li, P Alam, H Bai, V Bhalla, MR Bryce… - ACS …, 2023 - ACS Publications
Light has profoundly impacted modern medicine and healthcare, with numerous
luminescent agents and imaging techniques currently being used to assess health and treat …

Versatile types of inorganic/organic NIR-IIa/IIb fluorophores: from strategic design toward molecular imaging and theranostics

Y Liu, Y Li, S Koo, Y Sun, Y Liu, X Liu, Y Pan… - Chemical …, 2021 - ACS Publications
In vivo imaging in the second near-infrared window (NIR-II, 1000–1700 nm), which enables
us to look deeply into living subjects, is producing marvelous opportunities for biomedical …

Molecular probes for autofluorescence-free optical imaging

Y Jiang, K Pu - Chemical reviews, 2021 - ACS Publications
Optical imaging is an indispensable tool in clinical diagnostics and fundamental biomedical
research. Autofluorescence-free optical imaging, which eliminates real-time optical …

Supramolecular cancer nanotheranostics

J Zhou, L Rao, G Yu, TR Cook, X Chen… - Chemical Society …, 2021 - pubs.rsc.org
Among the many challenges in medicine, the treatment and cure of cancer remains an
outstanding goal given the complexity and diversity of the disease. Nanotheranostics, the …

The chemistry of organic contrast agents in the NIR‐II window

J Mu, M Xiao, Y Shi, X Geng, H Li… - Angewandte Chemie …, 2022 - Wiley Online Library
Optical imaging, especially fluorescence and photoacoustic imaging, is a non‐invasive
imaging approach with high spatial and temporal resolution and high sensitivity, compared …

Achieving efficient NIR‐II type‐I photosensitizers for photodynamic/photothermal therapy upon regulating chalcogen elements

K Wen, H Tan, Q Peng, H Chen, H Ma… - Advanced …, 2022 - Wiley Online Library
Second near‐infrared (NIR‐II) window type‐I photosensitizers have intrinsic advantages in
photodynamic/photothermal therapy (PDT/PTT) of some malignant tumors with deep …

Molecular engineering of NIR‐II fluorophores for improved biomedical detection

Z Lei, F Zhang - Angewandte Chemie International Edition, 2021 - Wiley Online Library
The development of fluorophores for the second near‐infrared window (NIR‐II, 1000–1700
nm) represents an emerging, significant, and vibrant field in analytic chemistry, chemical …

Long wavelength–emissive Ru (II) metallacycle–based photosensitizer assisting in vivo bacterial diagnosis and antibacterial treatment

Y Xu, C Li, X Ma, W Tuo, L Tu, X Li… - Proceedings of the …, 2022 - National Acad Sciences
Ruthenium (Ru) complexes are developed as latent emissive photosensitizers for cancer
and pathogen photodiagnosis and therapy. Nevertheless, most existing Ru complexes are …

First-in-human liver-tumour surgery guided by multispectral fluorescence imaging in the visible and near-infrared-I/II windows

Z Hu, C Fang, B Li, Z Zhang, C Cao, M Cai… - Nature biomedical …, 2020 - nature.com
The second near-infrared wavelength window (NIR-II, 1,000–1,700 nm) enables
fluorescence imaging of tissue with enhanced contrast at depths of millimetres and at …