[HTML][HTML] New methods used in pharmacokinetics and therapeutic monitoring of the first and newer generations of antiepileptic drugs (AEDs)

K Sommerfeld-Klatta, B Zielińska-Psuja… - Molecules, 2020 - mdpi.com
The review presents data from the last few years on bioanalytical methods used in
therapeutic drug monitoring (TDM) of the 1st–3rd generation and the newest antiepileptic …

Implementation of quality by design approach for optimization of the green voltammetric analysis of a brain doping agent (Piracetam) using a novel molecular …

PM Medhat, MM Fouad, AM Mahmoud… - Microchemical …, 2024 - Elsevier
It is encouraging to note that in recent years there has been a growth of high-quality articles
detailing molecular imprinted sensors for the detection of biomolecules, illicit narcotics, and …

[HTML][HTML] A new green approach for the reduction of consumed solvents and simultaneous quality control analysis of several pharmaceuticals using a fast and …

MA Abdelgawad, EA Abdelaleem, M Gamal… - RSC …, 2022 - pubs.rsc.org
One of the main aims of green analytical chemistry (GAC) is the reduction of solvents and
chemicals consumed. Recycling the mobile phase in chromatographic techniques provides …

Development of an Inexpensive, sensitive and green HPLC method for the simultaneous determination of brivaracetam, piracetam and carbamazepine; application to …

NM Mansour, DT El-Sherbiny, FA Ibrahim… - Microchemical …, 2021 - Elsevier
Racetams have recently become the most important adjunctive therapy in case of many
CNS disorders. The goal of the proposed method is to develop and validate a new green …

A simple and rapid spectrophotometric method coupled with intelligent approaches for the simultaneous determination of antiepileptic drugs in pharmaceutical …

R Noroozi, MR Sohrabi, M Davallo - Chemometrics and Intelligent …, 2022 - Elsevier
In this study, simultaneous measurement of Phenytoin (PHT), Levetiracetam (LEV), and
Pregabalin (PRG) was assessed by chemometrics methods, including feedforward artificial …

Validation of a specific Reversed-Phase HPLC method for the quantification of three racetams; Piracetam, Levetiracetam, and brivaracetam in the presence of Co …

NM Mansour, DT El-Sherbiny, FA Ibrahim… - Microchemical …, 2022 - Elsevier
A green, rapid, and sensitive reversed phase HPLC technique coupled with UV detection is
developed for the simultaneous determination of three structurally-related CNS active …

The use of separation techniques in the analysis of some antiepileptic drugs: a critical review

FA Mohamed, MF Bakr, AH Rageh… - Journal of Liquid …, 2016 - Taylor & Francis
In the last few decades, many new antiepileptic drugs came out to medicine world, and their
use was expanded over a wide range of cases. Analysts from all over the world developed …

Sensitive inexpensive HPLC determination of four antiepileptic drugs in human plasma: application to PK studies

FA Ibrahim, AF El-Yazbi, MA Barary, MM Wagih - Bioanalysis, 2016 - Taylor & Francis
Aim: Recently, polytherapy regimen has been introduced for the treatment of epileptic
patients for better seizure control with lesser side effects and better control of multiple …

Concurrent determination of diltiazem, lisinopril, captopril, and enalapril in dosage formulations and in human serum by liquid chromatographic technique

N Shafi, FA Siddiqui, N Sultana… - Journal of Liquid …, 2015 - Taylor & Francis
The aim of this study was to develop an analytical method that can quantify diltiazem,
lisinopril, captropil, and enalapril in pharmaceuticals dosage forms and biological fluids, as …

Chromatographic characterization and method development for determination of levetiracetam in saliva: application to correlation with plasma levels

II Hamdan, M Alsous, AT Masri - Journal of Analytical Methods …, 2017 - Wiley Online Library
Levetiracetam (LVT) is a widely used antiepileptic drug (AED). A less invasive sampling
method for therapeutic drug monitoring (TDM) would be very useful particularly for children …