Insulin signaling controls cell growth and metabolic homeostasis. Dysregulation of this
pathway causes metabolic diseases such as diabetes. Insulin signaling pathways have …

Insulin receptor (INSR) has been extensively studied in the area of cell proliferation and
energy metabolism. Impaired INSR activities lead to insulin resistance, the key factor in the …

Background Microbial inhabitants of soils are important to ecosystem and planetary
functions, yet there are large gaps in our knowledge of their diversity and ecology. The …

Insulin receptor (IR) signaling defects cause a variety of metabolic diseases including
diabetes. Moreover, inherited mutations of the IR cause severe insulin resistance, leading to …

Aging is attended by a progressive decline in protein homeostasis (proteostasis),
aggravating the risk for protein aggregation diseases. To understand the coordination …

Insulin controls glucose homeostasis and cell growth through bifurcated signaling pathways.
Dysregulation of insulin signaling is linked to diabetes and cancer. The spindle checkpoint …

The insulin receptor (IR) is a transmembrane protein that is activated by ligands in insulin
signaling pathways. The IR has been considered as a novel therapeutic target for clinical …

Diabetes refers to a group of metabolic diseases characterized by impaired insulin
signalling and high blood glucose. A growing body of epidemiological evidence links …

Association Between Cd Exposure and Risk of Prostate Cancer:... : Medicine Association
Between Cd Exposure and Risk of Prostate Cancer: A PRISMA-Compliant Systematic Review …

Insulin signaling is critical for the development of preovulatory follicles and progression
through the antral stage. Using a conditional knockout model that escapes this blockage, we …