Simple Summary Emerging evidence suggests positive outcomes from the use of CBD as a
cancer treatment. CBD can relieve cancer pain and ease the side effects of chemotherapy; …

More than fifty years after the 3Rs definition and despite the continuous implementation of
regulatory measures, animals continue to be widely used in basic research. Their use …

Cannabidiol (CBD) is an easily accessible and affordable Marijuana (Cannabis sativa L.)
plant derivative with an extensive history of medical use spanning thousands of years …

Exosomes are extracellular vesicles (EVs) originating from endosomes that play a role in
cellular communication. These vesicles which mimic the parental cells that release them are …

The significant resistance to currently available chemotherapeutics makes treatment for
TNBC a key clinical concern. Herein, we studied the anti-cancer potentials of synthetic …

Significance: Reactive oxygen species (ROS) are critical to normal cellular function with
redox homeostasis achieved by balancing ROS production with removal through …

Oral multitarget tyrosine kinase inhibitors (TKIs), such as sorafenib, which suppress tumor
cell proliferation and tumor angiogenesis, have been approved to treat patients with …

Triple-negative breast cancer (TNBC) is a highly heterogeneous disease with different
molecular subtypes. Although progress has been made, the identification of TNBC subtype …

Background Lung cancer (LC) is a malignancy with one of the highest mortality rates.
Respiratory microbiota is considered to play a key role in the development of LC, but the …

Background: In this study, we investigated in detail the role of cannabidiol (CBD), beta-
caryophyllene (BC), or their combinations in diabetic peripheral neuropathy (DN). The key …