The cardiovascular disease (CVD) pandemic has placed considerable strain on healthcare
systems, quality of life, and physical function, while remaining the leading cause of death …

Hypertrophic cardiomyopathy (HCM) has been considered a heterogeneous cardiac
disease ascribed solely to single sarcomere gene mutations. However, limitations of this …

In the realm of medicine, artificial intelligence (AI) has emerged as a transformative force,
harnessing the power to convert raw data into meaningful insights. Rather than supplanting …

Pulmonary hypertension is a complex disease with multiple causes, corresponding to
phenotypic heterogeneity and variable therapeutic responses. Advancing understanding of …

Advanced phenotyping of cardiovascular diseases has evolved with the application of high-
resolution omics screening to populations enrolled in large-scale observational and clinical …

Rationale: Pulmonary hypertension (PH) is a life-threatening cardiopulmonary disorder in
which inflammation and immunity have emerged as critical early pathogenic elements …

Background Cardiovascular disease is a leading cause of death in general population and
the second leading cause of mortality and morbidity in cancer survivors after recurrent …

The past decade has witnessed exponential growth in the generation of high-throughput
human data across almost all known dimensions of biological systems. The discipline of …

Network medicine can advance current medical practice by arising as response to the
limitations of a reductionist approach focusing on cardiovascular (CV) diseases as a direct …

The ability to generate multi-omics data coupled with deeply characterizing the clinical
phenotype of individual patients promises to improve understanding of complex …