1.1. General Considerations Structural intricacies of carbohydrate molecules and their
propensity to form varied linkages, substitutions, and branching patterns have fascinated …

The increasing scale and complexity of quantitative proteomics studies complicate
subsequent analysis of the acquired data. Untargeted label-free quantification, based either …

This review is the sixth update of the original article published in 1999 on the application of
MALDI mass spectrometry to the analysis of carbohydrates and glycoconjugates and brings …

Haptoglobin is a liver-secreted glycoprotein with four N-glycosylation sites. Its glycosylation
was reported to change in several cancer diseases, which prompted us to examine site …

Breast cancer is a highly heterogeneous disease. Its intrinsic subtype classification for
diagnosis and choice of therapy traditionally relies on the presence of characteristic …

Introduction: Aberrant glycosylation has been associated with many diseases. Decades of
research activities have reported many reliable glycan biomarkers of different diseases …

Aberrations in protein glycosylation and polysaccharides play a pivotal role in pancreatic
tumorigenesis, influencing cancer progression, metastasis, immuno-response and …

Mass spectrometry (MS) has been a core technology for high sensitive and high‐throughput
analysis of the enriched glycoproteome in aspects of quantitative assays as well as …

Lung adenocarcinoma (LAC) is the most common form of lung cancer that increases in non-
smokers at younger age. Altered protein glycosylation is one of the hallmarks of malignancy …

Proteomics study of pancreatic cancer using bodily fluids emphasizes biomarker discovery
and clinical application, presenting unique prospect and challenges. Depending on the …