Understanding the molecular basis of cardiomyopathy

ML Bang, J Bogomolovas… - American Journal of …, 2022 - journals.physiology.org
Inherited cardiomyopathies are a major cause of mortality and morbidity worldwide and can
be caused by mutations in a wide range of proteins located in different cellular …

KLF13 loss‐of‐function mutations underlying familial dilated cardiomyopathy

YH Guo, J Wang, XJ Guo, RF Gao… - Journal of the …, 2022 - Am Heart Assoc
Background Dilated cardiomyopathy (DCM), characterized by progressive left ventricular
enlargement and systolic dysfunction, is the most common type of cardiomyopathy and a …

Identification of BMP10 as a Novel Gene Contributing to Dilated Cardiomyopathy

JN Gu, CX Yang, YY Ding, Q Qiao, RM Di, YM Sun… - Diagnostics, 2023 - mdpi.com
Dilated cardiomyopathy (DCM), characterized by left ventricular or biventricular enlargement
with systolic dysfunction, is the most common type of cardiac muscle disease. It is a major …

Integrative analysis of genes reveals endoplasmic reticulum stress-related immune responses involved in dilated cardiomyopathy with fibrosis

W Li, P Liu, H Liu, F Zhang, Y Fu - Apoptosis, 2023 - Springer
Endoplasmic reticulum (ER) stress has been implicated in the mechanisms underlying the
fibrotic process in dilated cardiomyopathy (DCM) and results in disease exacerbation; …

[HTML][HTML] Selection of key genes for dilated cardiomyopathy based on machine learning algorithms and assessment of diagnostic accuracy

T Chen, X Xuan, J Ni, S Jiang - Journal of Thoracic Disease, 2023 - ncbi.nlm.nih.gov
Background The mechanisms of the occurrence and progression of dilated cardiomyopathy
are still unclear and further exploration is needed. The upgrading of programming …

Transcriptome analysis uncovers the autophagy‐mediated regulatory patterns of the immune microenvironment in dilated cardiomyopathy

S Sun, J Lu, C Lai, Z Feng, X Sheng… - Journal of Cellular …, 2022 - Wiley Online Library
The relationship between autophagy and immunity has been well studied. However, little is
known about the role of autophagy in the immune microenvironment during the progression …

Analysis of the disease burden of cardiomyopathy in children aged 0–14 years in China from 1990 to 2019

Q Kong, M Li, M Wang, H Zhao, X Yang… - Frontiers in Public …, 2023 - frontiersin.org
Objectives To assess the disease burden and changing trend of cardiomyopathy in children
aged 0–14 years in China from 1990 to 2019. Methods This study was based on the Global …

Serum microRNA-125b-5p expression in patients with dilated cardiomyopathy combined with heart failure and its effect on myocardial fibrosis

Y Zhang, D Deng, Q Huang, J Wu… - Scandinavian …, 2024 - Taylor & Francis
Objective This paper was performed to decipher the serum microRNA (miR)-125b-5p
expression in patients with dilated cardiomyopathy (DCM) combined with heart failure (HF) …

Identification and in silico characterization of CSRP3 synonymous variants in dilated cardiomyopathy

P Giri, D Jain, A Kumar, B Mohapatra - Molecular Biology Reports, 2023 - Springer
Background Synonymous variations have always been ignored while studying the
underlying genetic mechanisms for most of the human diseases. However, recent studies …

Association between MMP2 gene polymorphisms and dilated cardiomyopathy in a Chinese Han population

S Li, X Zeng, S Wang, X Xie, J Lan - ESC Heart Failure, 2023 - Wiley Online Library
Aims Dilated cardiomyopathy (DCM) belongs to the common types of cardiomyopathies. The
pathogenesis remains unclear despite the fact that various genes have been found …