Trabeculectomy with antifibrotic treatment is still the most popular incisional procedure for
glaucoma filtration surgery (GFS) worldwide. The advent of antifibrotic agents reduced …

The cornea is one of the few tissues which actively maintain an avascular state, ie the
absence of blood and lymphatic vessels (corneal [lymph] angiogenic privilege). Nonetheless …

Glaucoma is considered to be one of the biggest health problems in the world. It is the main
cause of preventable blindness due to its asymptomatic nature in the early stages on the …

Angiogenesis may pose a clinical challenge in glaucoma, for example, during the wound
healing phase after glaucoma filtration surgery and in the severe secondary glaucoma …

Despite the advent of many new devices for glaucoma surgery, scarring is the main cause of
suboptimal pressure control and surgical failure in all forms of surgery. The cytotoxic …

Subconjunctival fibrosis at the surgical site determines the outcome of glaucoma surgery.
Myofibroblast transformation has a significant role in fibrosis, and vascular endothelial …

The approval of one of the first anti-vascular endothelial growth factor (VEGF) agents for the
treatment of neovascular age-related macular degeneration one decade ago marked the …

Purpose: To compare the safety and efficacy of primary trabeculectomy with adjunctive
subconjunctival bevacizumab with that of primary trabeculectomy with mitomycin C (MMC) …

Importance The Tube vs Trabeculectomy Trial (TVT) found that the 350-mm 2 Baerveldt
implant (tube) and trabeculectomy with mitomycin may be similarly effective in lowering …

Ocular fibrosis leads to significant visual impairment and blindness in millions of people
worldwide, and is one of the largest areas of unmet need in clinical ophthalmology. The …