Substituted tetrahydrofurans are commonly occurring substructures found in a broad array of
natural products and other biologically active molecules. For example, the annonaceous …

Ever since the early discoveries that highly oxidized transition-metal reagents are able to
react with olefins to form oxidized organic compounds, chemists have investigated and …

Diastereoselective synthesis of 2,5-disubstituted tetrahydrofurans - ScienceDirect Skip to main
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In the last years ruthenium tetroxide is increasingly being used in organic synthesis. Thanks
to the fine tuning of the reaction conditions, including pH control of the medium and the use …

Asymmetric Permanganate-Promoted Oxidative Cyclization of 1,5-Dienes by Using Chiral
Phase-Transfer Catalysis This work was supported by the EPSRC (JFK) and the Royal Society …

Since its introduction into organic chemistry more than fifty years ago, RuO 4 has been used
mainly as a strong oxidizing agent. Owing to its high reactivity, catalytic reactions employing …

(Chemical Equation Presented) High yields and high levels of stereocontrol are observed in
the oxidative cyclization of vicinal diols using catalytic amounts of a transition metal (see …

An enantioselective total synthesis of cis-solamin has been accomplished using a highly
diastereoselective ruthenium tetroxide catalyzed oxidative cyclization as a crucial …

An efficient method has been developed for the synthesis of 2, 5-dialkyl-substituted
tetrahydrofurans, analogues of natural acetogenins. A series of tetrahydrofurans of this type …

An efficient total synthesis of cis-solamin (1) has been achieved in 21% overall yield and
with a longest linear sequence of just 11 steps from aldehyde 8. A key feature of the …