The ability to replace organs and tissues on demand could save or improve millions of lives
each year globally and create public health benefits on par with curing cancer. Unmet needs …

Acute kidney injury occurs with kidney transplantation and too frequently progresses to the
clinical diagnosis of delayed graft function (DGF). Poor kidney function in the first week of …

Background Hemodynamic instability and myocardial dysfunction are major factors
preventing the transplantation of hearts from organ donors after brain death. Intravenous …

Short-term patient and graft outcomes continue to improve after kidney and liver
transplantation, with 1-year survival rates over 80%; however, improving longer-term …

The challenges inherent in conducting accurate, clinically effective, and cost-effective
cardiac evaluations among transplantation candidates relate to the large size of the target …

This document was developed through the collaborative efforts of the Society of Critical Care
Medicine, the American College of Chest Physicians, and the Association of Organ …

Background Delayed graft function, which is reported in up to 50% of kidney-transplant
recipients, is associated with increased costs and diminished long-term graft function. The …

Context Antibody-based induction therapy plus calcineurin inhibitors (CNIs) reduce acute
rejection rates in kidney recipients; however, opportunistic infections and toxic CNI effects …

The main factor limiting organ donation is the availability of suitable donors and organs.
Currently, most transplants follow multiple organ retrieval from heartbeating brain-dead …

Purpose To provide a practical overview of the management of the potential organ donor in
the intensive care unit. Methods Seven areas of donor management were considered for this …