An update on human papilloma virus vaccines: history, types, protection, and efficacy

Z Yousefi, H Aria, F Ghaedrahmati, T Bakhtiari… - Frontiers in …, 2022 - frontiersin.org
Human papillomavirus (HPV) is the most common sexually transmitted agent worldwide.
Early prevention with HPV vaccination is a safe and effective method against this disease …

Lead SARS-CoV-2 candidate vaccines: expectations from phase III trials and recommendations post-vaccine approval

E Tumban - Viruses, 2020 - mdpi.com
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is transmitted primarily
through respiratory droplets/aerosols and it causes COVID-19. The virus infects epithelial …

Virus-like particle vaccines: immunology and formulation for clinical translation

B Donaldson, Z Lateef, GF Walker… - Expert review of …, 2018 - Taylor & Francis
Introduction: Virus-like particle (VLP) vaccines face significant challenges in their translation
from laboratory models, to routine clinical administration. While some VLP vaccines thrive …

Stability of lyophilized and spray dried vaccine formulations

KB Preston, TW Randolph - Advanced Drug Delivery Reviews, 2021 - Elsevier
Liquid formulations of vaccines are subject to instabilities that result from degradation
processes that proceed via a variety of physical and chemical pathways. In dried …

[HTML][HTML] Stabilizing vaccines via drying: Quality by design considerations

Z Ghaemmaghamian, R Zarghami, G Walker… - Advanced Drug Delivery …, 2022 - Elsevier
Pandemics and epidemics are continually challenging human beings' health and imposing
major stresses on the societies particularly over the last few decades, when their frequency …

Aerosol pulmonary immune engineering

ER Sudduth, M Trautmann-Rodriguez, N Gill… - Advanced Drug Delivery …, 2023 - Elsevier
Aerosolization of immunotherapies poses incredible potential for manipulating the local
mucosal-specific microenvironment, engaging specialized pulmonary cellular defenders …

RG1-VLP and other L2-based, broad-spectrum HPV vaccine candidates

B Huber, JW Wang, RBS Roden… - Journal of Clinical …, 2021 - mdpi.com
Licensed human papillomavirus (HPV) vaccines contain virus-like particles (VLPs) self-
assembled from L1 major-capsid proteins that are remarkably effective prophylactic …

Developments in the formulation and delivery of spray dried vaccines

G Kanojia, R Have, PC Soema, H Frijlink… - Human vaccines & …, 2017 - Taylor & Francis
Spray drying is a promising method for the stabilization of vaccines, which are usually
formulated as liquids. Usually, vaccine stability is improved by spray drying in the presence …

Spray drying and particle engineering in dosage form design for global vaccines

M Gomez, R Vehring - Journal of Aerosol Medicine and Pulmonary …, 2022 - liebertpub.com
Vaccines are a very important tool in the effort to reduce the global burden of infectious
diseases. Modern vaccines can be formulated in several ways to induce specific immunity …

Multicomponent solid dispersion a new generation of solid dispersion produced by spray-drying

LM De Mohac, B Raimi-Abraham, R Caruana… - Journal of Drug Delivery …, 2020 - Elsevier
The term “multicomponent solid dispersion” is widely used in recent literature to describe
solid formulations consisting of a special excipient's mixture and active molecules finely …