[HTML][HTML] Physiological role and use of thyroid hormone metabolites-potential utility in COVID-19 patients
E Fröhlich, R Wahl - Frontiers in endocrinology, 2021 - frontiersin.org
Thyroxine and triiodothyronine (T3) are classical thyroid hormones and with relatively well-
understood actions. In contrast, the physiological role of thyroid hormone metabolites, also …
understood actions. In contrast, the physiological role of thyroid hormone metabolites, also …
[HTML][HTML] Thyroid hormone regulates adhesion, migration and matrix metalloproteinase 9 activity via αvβ3 integrin in myeloma cells
K Cohen, N Flint, S Shalev, D Erez, T Baharal… - Oncotarget, 2014 - ncbi.nlm.nih.gov
Abstract Thyroid hormone (3, 5, 3′-triiodothyronine, T3; L-thyroxine, T4) enhances cancer
cell proliferation, invasion and angiogenesis via a discrete receptor located near the RGD …
cell proliferation, invasion and angiogenesis via a discrete receptor located near the RGD …
[HTML][HTML] Tetrac as an anti-angiogenic agent in cancer
KA Schmohl, PJ Nelson… - Endocrine-Related …, 2019 - erc.bioscientifica.com
The thyroid hormones T3 and T4 have emerged as pro-angiogenic hormones with important
implications for cancer management. Endogenous circulating hormone levels may help …
implications for cancer management. Endogenous circulating hormone levels may help …
[HTML][HTML] Mammalian target of rapamycin inhibition abrogates insulin-mediated mammary tumor progression in type 2 diabetes
Y Fierz, R Novosyadlyy, A Vijayakumar… - Endocrine-related …, 2010 - erc.bioscientifica.com
Type 2 diabetes increases breast cancer risk and mortality, and hyperinsulinemia is a major
mediator of this effect. The mammalian target of rapamycin (mTOR) is activated by insulin …
mediator of this effect. The mammalian target of rapamycin (mTOR) is activated by insulin …
Thyroid hormone effects on mesenchymal stem cell biology in the tumour microenvironment
KA Schmohl, AM Müller, PJ Nelson… - Experimental and …, 2020 - thieme-connect.com
Non-classical thyroid hormone signalling via cell surface receptor integrin αvβ3, expressed
on most cancer cells and proliferating endothelial cells, has been shown to drive tumour cell …
on most cancer cells and proliferating endothelial cells, has been shown to drive tumour cell …
Synthesis and characterization of 64Cu-and Cy5. 5-labeled tetraiodothyroacetic acid derivatives for tumor angiogenesis imaging
It was previously reported that tetraiodothyroacetic acid (tetrac) inhibits angiogenesis by
binding to the cell surface receptor for thyroid hormone on integrin α V β 3. Therefore, we …
binding to the cell surface receptor for thyroid hormone on integrin α V β 3. Therefore, we …