MicroRNAs and the diagnosis of childhood acute lymphoblastic leukemia: systematic review, meta-analysis and re-analysis with novel small RNA-seq tools

I Kyriakidis, K Kyriakidis, A Tsezou - Cancers, 2022 - mdpi.com
Simple Summary MicroRNAs (miRNAs) have been under the spotlight for the last three
decades. These non-coding RNAs seem to be dynamic regulators of mRNA stability and …

Implication of microRNAs in carcinogenesis with emphasis on hematological malignancies and clinical translation

Z Gaál - International Journal of Molecular Sciences, 2022 - mdpi.com
MicroRNAs (miRNAs) are evolutionarily conserved small non-coding RNAs, that are
involved in the multistep process of carcinogenesis, contributing to all established hallmarks …

[HTML][HTML] A novel PTEN mutant caused by polymorphism in cis-regulatory elements is involved in chemosensitivity in breast cancer

J Wang, S Zhang, J Zhang, Z Zhang, Q Ma… - American Journal of …, 2023 - ncbi.nlm.nih.gov
Phosphatase and tensin homolog (PTEN) is one of the most important tumor suppressor
genes. Although studies have shown the association between cancer and genetic …

Novel polymorphism rs12402181 in the mature sequence of hsa-miR-3117-3p has a protective effect against breast cancer development by affecting miRNA …

R Mirabbasi, SO Ebrahimi, F Tavakoli, S Reiisi - 3 Biotech, 2023 - Springer
The current study aimed to investigate how the rs12402181 variant in the miR-3117-3p seed
region affects miRNA processing and binding ability to the target sequences and breast …

miRNA deregulation in childhood acute lymphoblastic leukemia: A systematic review

A Gutierrez-Camino, S Garcia-Obregon… - …, 2020 - Taylor & Francis
Despite remarkable improvements in survival of childhood acute lymphoblastic leukemia
(ALL), nonresponding or relapsing patients still represent one of the most frequent causes of …

Serum miR‑338‑5p has potential for use as a tumor marker for retinoblastoma

P Zhou, X Li - Oncology Letters, 2019 - spandidos-publications.com
The aim of the present study was to investigate the expression of microRNA (miR)‑338‑5p in
retinoblastoma (RB), thereby evaluating whether it could have potential as a biomarker to …

Association of genetic polymorphisms of miR-145 gene with telomere length in omethoate-exposed workers

W Wang, H Zhang, X Duan, X Feng, T Wang… - Ecotoxicology and …, 2019 - Elsevier
Omethoate, an organophosphorous pesticide, causes a variety of health effects, especially
the damage of chromosome DNA. The aim of the study was to assess the correlation …

Genetic parameter estimates and identification of SNPs associated with growth traits in Senegalese sole

I Guerrero-Cózar, E Jimenez-Fernandez, C Berbel… - Aquaculture, 2021 - Elsevier
Breeding programs are essential for aquaculture. The present study was conducted to
investigate the genetic parameters of four growth traits in Senegalese sole. Families were …

Impact of microRNA polymorphisms on high-dose methotrexate-related hematological toxicities in pediatric acute lymphoblastic leukemia

M Zhan, T Liu, Z Zhang, G Wang, Z Cao, X Li… - Frontiers in …, 2023 - frontiersin.org
Objectives It is well known that transporter and enzyme genes could be regulated by
microRNA (miRNA) at the post-transcriptional level, and single-nucleotide polymorphisms …

Association of MIR3117 and MIR612 genes polymorphisms with childhood acute lymphoblastic leukemia in the Mexican population

MF Ayón-Pérez, Y Gómez-Gómez… - Archives of Medical …, 2022 - Elsevier
Introduction Acute lymphoblastic leukemia (ALL) is the most common childhood cancer in
the world, which is associated with a wide spectrum of factors that play an important role in …