ABC transporters are essential for cellular physiology. Humans have 48 ABC genes
organized into seven distinct families. Of these genes, 44 (in five distinct families) encode for …

The ATP‐binding cassette (ABC) transporter superfamily comprises membrane proteins that
efflux various substrates across extra‐and intracellular membranes. Mutations in ABC genes …

AMD is a major cause of legal blindness in older adults approachable through
multidisciplinary research involving human tissues and patients. AMD is a vascular …

Cardiovascular complications due to accelerated arterial stiffening and atherosclerosis are
the leading cause of morbimortality in Western society. Both pathologies are frequently …

Non-exudative macular and choroidal neovascularization (MNV and CNV) usually refers to
the entity of treatment-naïve type 1 neovascularization in the absence of associated signs of …

This article explores contemporary biopolitics in the light of Michel Foucault's oft quoted
suggestion that contemporary politics callslife itself'into question. It suggests that recent …

Chemotherapeutics are the most effective treatment for metastatic tumours. However, the
ability of cancer cells to become simultaneously resistant to different drugs—a trait known as …

The transport of specific molecules across lipid membranes is an essential function of all
living organisms and a large number of specific transporters have evolved to carry out this …

Purpose: Basal laminar deposit (BLamD) is a consistent finding in age-related macular
degeneration (AMD). We quantified BLamD thickness, appearance, and topography in eyes …

Bruch's membrane (BM) is a unique pentalaminar structure, which is strategically located
between the retinal pigment epithelium (RPE) and the fenestrated choroidal capillaries of …